Protein Alignment Sf3b3 and cpsf-1

DIOPT Version :9

• Sequence 1: NP_728546.1
• Gene: Sf3b3 / 38093
• FlyBaseID: FBgn0035162
• Length: 1227
• Species: Drosophila melanogaster
• Sequence 2: NP_500157.2
• Gene: cpsf-1 / 177003
• WormBaseID: WBGene00022301
• Length: 1454
• Species: Caenorhabditis elegans
• Alignment Length: 1525
• Identity: 296/1525 - (19%)
• Similarity: 520/1525 - (34%)
• Gaps: 416/1525 - (27%)

  Fly     1 MYLYNLTLQKATGVTHAVHGNFSGGKQQ--EVLLSRGKSLELLRPD--------------SNTGK 49
            ||.|......:|.:..:.:|.|..|:..  ::|....|.:.:.|.:              ....|
 Worm     1 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVNPYVLKEPGEDNEEWQQKTK 65

  Fly    50 VHTLLSTEIFGCVRALMAFRLTG-GTKDYIVVGSDSGRIVILEYNPSKNALEKVHQETFG----K 109
            :..:.|..:.....::...|:.. ..:|.|::..|..::.|:..|..:..::.:....|.    :
 Worm    66 LECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERNMQTISLHAFENEYLR 130

  Fly   110 SGCRRIVPGQYFAIDPKGRAVMIGAVEKQKLAYIMNRDTQARL-TISSPL---EAHKSNTLTYHM 170
            .|............||..|.... .|..:.:|.:...:...|: :...||   :....|..  .|
 Worm   131 DGFINHFQPPLVRSDPSNRCAAC-LVYGKHIAILPFHENSKRIHSYVIPLKQIDPRLDNIA--DM 192

  Fly   171 VGVDVGFDNPMFACLEIDYEEADMDPSGDAAQRTQQTLTFYELDLGLNHVVRKYSE-------PL 228
            |.:| |:..|....|   ||.....| |.|..|..   |...:.:.:|.|.|:::.       |:
 Worm   193 VFLD-GYYEPTILFL---YEPIQTTP-GRACVRYD---TMCIMGVSVNIVDRQFAVVWQTANLPM 249

  Fly   229 EEHANFLVSVPGGNDGP-SGVLICSENYLTYKN---------LGDQHDIRCPIPRRRNDLDDPER 283
            :  .:.|:.:|    .| .|.|:...|.:.|.|         |...:|.....|.:    |....
 Worm   250 D--CSQLLPIP----KPLGGALVFGSNTVVYLNQAVPPCGLVLNSCYDGFTKFPLK----DLKHL 304

  Fly   284 GMIFICSATHRTKSMYF----FLLQTEQGDIFKITLETDD--DVVSEIKL-KYFDTVPPATAMCV 341
            .|...||.     |:|.    ..:.:..||:|.:.|.|..  ..|..::. |.::| ..|.::.|
 Worm   305 KMTLDCST-----SVYMEDGRIAVGSRDGDLFLLRLMTSSGGGTVKSLEFSKVYET-SIAYSLTV 363

  Fly   342 LKTGFLFVASEFGNHYLYQIAHLG------------------------DDDDEPEFSSAMPLEEG 382
            ...|.|||.|..|:..|.:...|.                        |:||...:..|:..::.
 Worm   364 CAPGHLFVGSRLGDSQLLEYTLLKTTRDCAVKRLKIDNKDPAAAEIELDEDDMELYGGAIEEQQN 428

  Fly   383 ETFFFAPRALKNLVLVDELPSFAPI----------ITSQVADLANEDTP-QLYVLCGRGPRSTLR 436
            :.......:|:...| |.|.:..|:          :::.:.|....|.. .|....|.|....|.
 Worm   429 DDDEQIDESLQFREL-DRLRNVGPVKSMCVGRPNYMSNDLVDAKRRDPVFDLVTASGHGKNGALC 492

  Fly   437 VLRHGLEVSEMAVSELPGNPNAVWTVKKRADDEFDAYIIVSFVNATLVLSIGETVEEVTDSGFLG 501
            |.:..|. .|:..|.|......:|.| .|.::|...|:|||.|.:||:|.:||.:.|:.:..|:.
 Worm   493 VHQRSLR-PEIITSSLLEGAEQLWAV-GRKENESHKYLIVSRVRSTLILELGEELVELEEQLFVT 555

  Fly   502 TTPTLCCAALGDDAL-VQVYPDGIRHIRSDKRVNEWKAPGKKSITKCAVNQRQV-VITLSGRELV 564
            ..||:....|...|| |||....|..:...:::.|........:.:.::....| ::|.:||.|:
 Worm   556 GEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVIQASIVDPYVALLTQNGRLLL 620

  Fly   565 Y-FEMDPTGELNEYTERSEMPAEIMCMALGTVPEGEQRSWFLAVGLADNTVRILSL----DPNNC 624
            | ..|:|..:|.|        .:|...:..|        |.   ..|.|..::.|:    |.:..
 Worm   621 YELVMEPYVQLRE--------VDISATSFAT--------WH---ATAQNLTQLTSISIYADASEI 666

  Fly   625 LTPCSMQ----------ALPSPAESLCLVEMGHTESTTQGGLDDDAPAQRSGNNKGTIY-LNIGL 678
            :...:.:          ...|.||:..:.:..|.|:....|.|||.   ..|:...||. .|..:
 Worm   667 MKFAAAEKSMGGGGGGDGEVSTAENAMMKKEQHEEAILLHGEDDDF---LYGDEDETIMEQNFPV 728

  Fly   679 SNGVLLRTVLDPVSGDLADTRTR-YLGSRPVKLFRIKMQGSEAVLAMS-SRT------WLSYYHQ 735
            .||.  .|:..      ::||.| .||...::..|    |.|...|:. :||      ||...|:
 Worm   729 ENGE--ATIKQ------SNTRKRKRLGHDAIQSSR----GGEQSDAIDPTRTFSSISHWLIVSHE 781

  Fly   736 N------------------RFHLTP-----LSYETLEYASGFSSEQCS-EGIV----AISTNT-- 770
            |                  ||...|     |:.|..|......::|.: |..|    |...||
 Worm   782 NGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVEEEEKERKAKAQQAAKEASVPTDEAEQLNTEM 846

  Fly   771 ----LRILALEKLGAVFNQVAFPL----------------------------------------- 790
                .|:|..:.:|...|| |.|:
 Worm   847 KQLCERVLEAQIVGMGINQ-AHPILMAIVDEQVVLYEMFSSSNPIPGHLGISFRKLPHFICLRTS 910

  Fly   791 -------QYTP---------RTFVIHP-------DTGRMLI------------------------ 808
                   :..|         |..:|||       :.|.|::
 Worm   911 SHLNSDGKRAPFEMKINNGKRFSLIHPFERVSSVNNGVMIVGAVPTLLVYGAWGGMQTHQMTVDG 975

  Fly   809 ---AETDHN--------AYTEDTKSARKEQMAEEMRSAA----GDEER-------ELAREMANAF 851
               |.|..|        .|....||        |:|.|.    .|.|.       |:.|.:.:
 Worm   976 PIKAFTPFNNENVLHGIVYMTQHKS--------ELRIARMHPDFDYEMPYPVKKIEVGRTIHH-- 1030

  Fly   852 INEVLPEDVF----SSPKAGLGLW---------------------ASQIRCLDAMHGQTMFSVPL 891
            :..::..||:    |.||....:|                     |.....|:....|...:||.
 Worm  1031 VRYLMNSDVYAVVSSIPKPSNKIWVVMNDDKQEEIHEKDENFVLPAPPKYTLNLFSSQDWAAVPN 1095

  Fly   892 TQ-----NEAIMS---MAMLKFSIAADGRYYLAVG----IAKDLQLNPRISQGGCIDIY-KIDPT 943
            |:     .||:.:   :|:...|..:.....||:|    ..:::.:..||.....|::. :.|..
 Worm  1096 TEISFEDMEAVTACEDVALKSESTISGLETLLAMGTVNNYGEEVLVRGRIILCEVIEVVPEPDQP 1160

  Fly   944 CSSLEFMHRTDIDE---IPGALCGFQGRLLAGCGRMLRIYDFGKKKMLRKCENKHIPYQIVNIQA 1005
            .|:.:.....|.::   :.| ||...|.||.|.|:.:.|:.| |...|.......:.|.:..:.:
 Worm  1161 TSNRKIKVLFDKEQKGPVTG-LCAINGLLLCGMGQKVFIWQF-KDNDLMGISFLDMHYYVYQLHS 1223

  Fly  1006 MGHRVYVSDVQESVFFIRYRRAENQLIIFADD----THPRWVTATTLLD--YDTIAIADKFGNLS 1064
            :.......|.:||:..||::.....:.|.:.|    ..|. :.:..::|  :....::|:.||::
 Worm  1224 LRTIAIACDARESMSLIRFQEDNKAMSIASRDDRKCAQPP-MASQLVVDGAHVGFLLSDETGNIT 1287

  Fly  1065 IQRLPHSVTDDVDEDPTGTKSLWDRGLLSGASQKSENICSF-----HVGEIIMSLQKATLIPGGS 1124
            :    .:...:..|...|     :|..:..|.....||.:|     |...:.::.:..      .
 Worm  1288 M----FNYAPEAPESNGG-----ERLTVRAAINIGTNINAFVRLRGHTSLLQLNNEDE------K 1337

  Fly  1125 EAL------IYATLSGTVGAFVPFTSREDYDFFQHLEMHMRNENPPLCGRDHLSYRSSYYP---- 1179
            ||:      ::|:|.|:.|...|.|.: .|.....|:..:.:..|.:.|. |:....|..|
 Worm  1338 EAIEQRMTTVFASLDGSFGFVRPLTEK-SYRRLHFLQTFIGSVTPQIAGL-HIKGSRSAKPSQPI 1400

  Fly  1180 -----VKNVLDGDLCEQYLSIEAAKQKSIA 1204
                 .:|::|||:.||||.:....:..:|
 Worm  1401 VNGRNARNLIDGDVVEQYLHLSLYDKTDLA 1430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sf3b3	NP_728546.1	MMS1_N	76..592	CDD:402179	125/585 (21%)
		CPSF_A	872..1194	CDD:397339	74/363 (20%)
cpsf-1	NP_500157.2	SFT1	10..1447	CDD:227490	293/1516 (19%)
		MMS1_N	93..623	CDD:287414	120/559 (21%)
		CPSF_A	1079..1420	CDD:281209	73/360 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910