Protein Alignment CG13895 and tigd3

DIOPT Version :10

• Sequence 1: NP_001261220.1
• Gene: CG13895 / 38087
• FlyBaseID: FBgn0035158
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001128294.1
• Gene: tigd3 / 100135169
• XenbaseID: XB-GENE-6457180
• Length: 595
• Species: Xenopus tropicalis
• Alignment Length: 608
• Identity: 113/608 - (18%)
• Similarity: 194/608 - (31%)
• Gaps: 189/608 - (31%)

  Fly    18 NSNGSH---RIRNVLTLEERVAAIRQYDIVPM----YSKIARNFNCSWEQIKSIVSNREAILEFH 75
            |...||   :.|...||.|:|..:   :::..    .|.:|||...|...|..::.|||.|:|
 Frog     9 NPGASHQPFKKRRDSTLAEKVKIL---ELLQQPKASQSSVARNLGLSQSTISRVMKNREEIME-- 68

  Fly    76 KATNRLSQPANKDAELRRRKLNF--LGHCLYEYIQRAQFYLHSDVNE-----EMIRNRAIEFRDL 133
             ..|:...||.|    |.|....  :...|.|::      |.:..|:     .::..||......
 Frog    69 -RWNQNENPARK----RNRPFKHAKVDEALLEWL------LFAKANKLPISGPILMRRAEAIAKE 122

  Fly   134 MQLDGFVPNKPWINHFKAAYNITLSNRQITIVRRPPRSMDLRDI----MSYCGRHTSMSCSLAPR 194
            :....|.|:..|:..:|..|.: ....::...:|....:..:|:    ::| .:.|:....|...
 Frog   123 IGCPQFKPSNGWLWRWKERYRL-FYRTEVLPCQRSGMILQGQDVPESEIAY-DKVTAKGYCLGAN 185

  Fly   195 SPEPALTSS---DR-----PLYRTKTL---------------VTTSSQNQATSDEVHLRRKRKLA 236
            .....||.|   ||     |..|:.||               :.:..|.:|.:.:..:...:|.:
 Frog   186 ERSEVLTRSEFHDRSSQGCPRNRSLTLAQVAKEYHSQDIFCGIESPFQFRAMAGQGFMSEHKKES 250

  Fly   237 FLEKCVYEYIQRSQLVRQGRLDLDNLRFVAISLRDILKIDSFFPDKVWLKHFKSRYNFNFTVGVQ 301
            .   |::.....:...:...|...||...:|....:..:           ..|..:|...|.|:.
 Frog   251 V---CIWFCCNMNGTEKLKLLVTHNLPAKSIGANSLSPV-----------FLKLSHNGYLTEGLL 301

  Fly   302 V------------TNRRLPLSL---------DLRDIVSYC--GRNEHKITLDHKKSQEELSQ--- 340
            :            .:|::.|.|         .||:| |.|  .:|.......|...||.:|:
 Frog   302 IEWLLTWDSKLARQDRKVLLFLMAHSTVPKVKLRNI-SLCLFPKNNTNTPSSHLFGQELISEFNA 365

  Fly   341 ----------SDKPEVDQ------------------------------------CPQVEPKPEEF 359
                      .:.|.|.:                                    |.|.....:.|
 Frog   366 LYKQLLLDRFQEDPNVSRGSGVSFLRQLSHLSLVEASYTMNKAWLRISSYTIKNCFQKILSTQAF 430

  Fly   360 EHEEDDDCVAIEVPPELIEIKDDEDNDDEHNDNEDLP----ERATKRKSDENGGPIPCGLKIQKI 420
                   |.|...|..||             .|:|||    :.||:..  .|.||...||...:.
 Frog   431 -------CSARPQPTSLI-------------PNKDLPTLMLQGATENL--HNYGPFTAGLGTYRK 473

  Fly   421 QSLNESLPEDTELLPANSPGHYSETSDEAHLPRCVESYKDALRLLKPLEEF----VLMEENYRAI 481
            .::.|....:.|           |..||........||  .::.::..|:.    |..|.|....
 Frog   474 VTIKEECVVEQE-----------EEDDEFEASSSYLSY--PIQKVEDNEDMVHGGVKTERNCFDP 525

  Fly   482 GLLTQLEKIFESAAKKSEEMDKS 504
            .:.|:.:|:..:...|||.::.|
 Frog   526 CVTTKDKKMASAVGIKSEVLEDS 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13895	NP_001261220.1	CENP-B_N	24..74	CDD:461229	15/53 (28%)
		CENPB	93..159	CDD:197828	12/72 (17%)
		CENPB	232..298	CDD:197828	8/65 (12%)
tigd3	NP_001128294.1	Csa3	18..>138	CDD:442641	31/135 (23%)
		CENPB	83..147	CDD:197828	11/70 (16%)
		DDE_3	248..421	CDD:481203	25/187 (13%)