DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13894 and THAP3

DIOPT Version :10

Sequence 1:NP_612054.1 Gene:CG13894 / 38086 FlyBaseID:FBgn0035157 Length:528 Species:Drosophila melanogaster
Sequence 2:NP_001381425.1 Gene:THAP3 / 90326 HGNCID:20855 Length:246 Species:Homo sapiens


Alignment Length:287 Identity:56/287 - (19%)
Similarity:101/287 - (35%) Gaps:73/287 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 RRCCIIGCLSNSRQHPSMQFFAFPRPENPFHKLWKE-ACHASLRRIVPFKKPVVCALHFDP---S 65
            |:||  ...|:.|:..:...|.|.|||     |.|| ..:.......|.:..|:|:.||.|   |
Human     8 RQCC--NRYSSRRKQLTFHRFPFSRPE-----LLKEWVLNIGRGNFKPKQHTVICSEHFRPECFS 65

  Fly    66 VLGGRR-LQSNALPTL------RLEVPSNLEAVEQQ--AMVEEIERSRKCAYINAVVYEWLVRAN 121
            ..|.|: |:.||:||:      ..:|..|.:...::  |...:.|::..|            |:.
Human    66 AFGNRKNLKHNAVPTVFAFQDPTQQVRENTDPASERGNASSSQKEKTSPC------------RSQ 118

  Fly   122 INPQL-RGSITHGMIKDKAENARQVIGSTSFIADNRWLNRFRETHLQGFAQKLASNQLKPLGSSL 185
            :.|:. .|..:.|...|.|....|:                 ..:.:|..::::..:        
Human   119 VLPEAGAGEDSPGRNMDTALEELQL-----------------PPNAEGHVKQVSPRR-------- 158

  Fly   186 WIPDIVQDLAHLFPPASAERVAKLEEMPEQYMTYMQQYGEYEEDDDSMDVKEQSYQEQQQQQQQH 250
              |...:.:.....||...|....:.....|...         |.||:  |::.:...::.::..
Human   159 --PQATEAVGRPTGPAGLRRTPNKQPSDHSYALL---------DLDSL--KKKLFLTLKENEKLR 210

  Fly   251 FALQQQHMQQQQHQMGHPWPPFPGHPG 277
            ..||.|.:..:  :|........||.|
Human   211 KRLQAQRLVMR--RMSSRLRACKGHQG 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13894NP_612054.1 THAP 6..82 CDD:214951 26/86 (30%)
CENPB 104..165 CDD:197828 8/61 (13%)
THAP3NP_001381425.1 THAP 5..82 CDD:461662 27/80 (34%)

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