Protein Alignment CG13894 and THAP2

DIOPT Version :10

• Sequence 1: NP_612054.1
• Gene: CG13894 / 38086
• FlyBaseID: FBgn0035157
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_113623.1
• Gene: THAP2 / 83591
• HGNCID: 20854
• Length: 228
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 56/259 - (21%)
• Similarity: 111/259 - (42%)
• Gaps: 59/259 - (22%)

  Fly     1 MPTIRRCCIIGCLSNSRQHPSMQFFAFP-RPENPFHKLWKEACHASLRRIVPFKKPVVCALHFDP 64
            |||  .|...||.:...:|.::.|..|| .|:.  .|.|......  :..||.|...:|:.||:.
Human     1 MPT--NCAAAGCATTYNKHINISFHRFPLDPKR--RKEWVRLVRR--KNFVPGKHTFLCSKHFEA 59

  Fly    65 SV--LGG--RRLQSNALPTLRLEVPSNLEAVEQQAMVEEIERSRKCAYINAVVYEWLVRANINPQ 125
            |.  |.|  |||:.:|:||: .:..:::::::.::. ..::::..|:.....    .:::||:.|
Human    60 SCFDLTGQTRRLKMDAVPTI-FDFCTHIKSMKLKSR-NLLKKNNSCSPAGPS----NLKSNISSQ 118

  Fly   126 LRGSITHG-MIKDKAENARQVIGSTSFIADNRWLNRFRETHLQG-------------FAQKLASN 176
             :..:.|. ..::..|..:::|.....||.   |.|..:|.||.             ..:.|.:|
Human   119 -QVLLEHSYAFRNPMEAKKRIIKLEKEIAS---LRRKMKTCLQKERRATRRWIKATCLVKNLEAN 179

  Fly   177 QLKPLGSSLWIPDIVQDLAHLFPPASAERVAKLEEMPEQYMTYMQQYGEYEEDDD---SMDVKE 237
            .:.|.|:|          .|:.|.|       |..:|.:....::|    ::.|.   |:::|:
Human   180 SVLPKGTS----------EHMLPTA-------LSSLPLEDFKILEQ----DQQDKTLLSLNLKQ 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13894	NP_612054.1	THAP	6..82	CDD:214951	25/80 (31%)
		CENPB	104..165	CDD:197828	11/61 (18%)
THAP2	NP_113623.1	THAP	5..80	CDD:461662	25/79 (32%)
		HCFC1-binding motif (HBM). /evidence=ECO:0000250	123..126		1/2 (50%)