Protein Alignment CG13894 and THAP7

DIOPT Version :10

• Sequence 1: NP_612054.1
• Gene: CG13894 / 38086
• FlyBaseID: FBgn0035157
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_085050.2
• Gene: THAP7 / 80764
• HGNCID: 23190
• Length: 309
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 61/320 - (19%)
• Similarity: 106/320 - (33%)
• Gaps: 99/320 - (30%)

  Fly     1 MPTIRRCCIIGCL---SNSRQHPSMQFFAFPRPENPFHKLWKEACHASLRRIVPFKKPV------ 56
            ||  |.|...||.   :...::..:.|...|:.:||...||...|    :|:.|..:.:
Human     1 MP--RHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANC----QRLDPSGQGLWDPASE 59

  Fly    57 ---VCALHFDP------SVLGGRRLQSNALPTL-----RLEVPSNLEAVEQQAMVEEIERSRKC- 106
               .|:.||:.      .:.|..||:..|:||:     :|...:..:.........|:.|.|:|
Human    60 YIYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRLRRCR 124

  Fly   107 ------------------AYINAV-VYEWLVRANINPQLRGSITHGMIKDKAENARQVIGSTSFI 152
                              |.:... |.|....|.:.....|.:..|:....::    ::|.....
Human   125 KRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSD----LLGPLGAQ 185

  Fly   153 ADNRWLNRFRETHLQGFAQKLASNQLKPLGSSLWIPDIVQDLAHLF---PPASAERVAKLEEMPE 214
            ||....:          ||.....|..||.     |..|...|::.   |||.|
Human   186 ADEAGCS----------AQPSPERQPSPLE-----PRPVSPSAYMLRLPPPAGA----------- 224

  Fly   215 QYMTYMQQYGEYEEDD------------DSMDVKEQSYQEQQQQQQQHFALQQQHMQQQQ 262
                |:|....|:...            |::| |.|...:..::::|...|:...:||::
Human   225 ----YIQNEHSYQVGSALLWKRRAEAALDALD-KAQRQLQACKRREQRLRLRLTKLQQER 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13894	NP_612054.1	THAP	6..82	CDD:214951	21/98 (21%)
		CENPB	104..165	CDD:197828	11/80 (14%)
THAP7	NP_085050.2	THAP	4..93	CDD:214951	21/92 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..209		11/69 (16%)
		HCFC1-binding motif (HBM). /evidence=ECO:0000250	229..232		0/2 (0%)