DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13894 and Thap2

DIOPT Version :9

Sequence 1:	NP_612054.1	Gene:	CG13894 / 38086	FlyBaseID:	FBgn0035157	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_001381922.1	Gene:	Thap2 / 688019	RGDID:	1593643	Length:	217	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	58/273 - (21%)
Similarity:	96/273 - (35%)	Gaps:	95/273 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPTIRRCCIIGCLSNSRQHPSMQFFAFP-RPENPFHKLWKEACHASLRRIVPFKKPVVCALHFDP 64
            |||  .|...||.:...:|.::.|..|| .|:.  .|.|......  :..||.|...:|:.||:.
  Rat     1 MPT--NCAAAGCAATYNKHINISFHRFPLDPKR--RKEWVRLVRR--KNFVPGKHTFLCSKHFEA 59

  Fly    65 SV--LGG--RRLQSNALPT----------LRLEV--------------PSNLEA-VEQQAMVEEI 100
            |.  |.|  |||:.:|:||          |:|:.              |.||:. ..||.::|
  Rat    60 SCFDLTGQTRRLKMDAVPTIFDFCTHIKSLKLKSRNLLKKSNSFTSAGPCNLKLNSSQQVLLE-- 122

  Fly   101 ERSRKCAYINAVVYEWLVRANINPQLR--------GSITHGMIKDKAENARQVIGSTSFIADNRW 157
                         :.:..|:.:..:.|        .|:...| |...:..|:        |..||
  Rat   123 -------------HSYAFRSPVEAKKRIIKLEREIASLRRKM-KTCLQRERR--------ATRRW 165

  Fly   158 LNRFRETHLQGFAQKLASNQLKPLGSSLWIPDIVQDLAHLFPPASAERVAKLEEMPEQYMTYMQQ 222
            :.      ...|.:.|.:..:.|.|.|          ..:.|.|       |..:|.:.:..:||
  Rat   166 IK------ATCFVKSLEAGNMLPKGIS----------EQILPTA-------LSSLPLENLKILQQ 207

  Fly   223 YGEYEEDDDSMDV 235
                ::.|.::.|
  Rat   208 ----DQQDKTLPV 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13894	NP_612054.1	THAP	6..82	CDD:214951	26/90 (29%)
		CENPB	104..165	CDD:197828	9/68 (13%)
		NST1	382..>468	CDD:290656
Thap2	NP_001381922.1	THAP	6..80	CDD:398893	24/77 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338628
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930