DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Vti1a and VTI1B

DIOPT Version :9

Sequence 1:	NP_612053.1	Gene:	Vti1a / 38085	FlyBaseID:	FBgn0260862	Length:	230	Species:	Drosophila melanogaster
Sequence 2:	NP_564255.1	Gene:	VTI1B / 839208	AraportID:	AT1G26670	Length:	222	Species:	Arabidopsis thaliana

Alignment Length:	212	Identity:	60/212 - (28%)
Similarity:	110/212 - (51%)	Gaps:	5/212 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLEQYEQQYATLIAEITAHIGRLQQQNNNSERHDLCSKIDSSLPEAQELLEQMGLEVRELNPGLR 67
            :.|.||:||..|...::.........:|..|:....::|.|.:.||..|:.:|.||.|.|.|..:
plant     4 VFEGYERQYCELSTNLSRKCHSASVLSNGEEKKGKIAEIKSGIDEADVLIRKMDLEARSLQPSAK 68

  Fly    68 SSFNGKLQVAQAELKRLQAEYR--LTKDKQRSQANTFTTLDLGDSYEDVSISTDQRQRLLDNSER 130
            :....||:..:::|.:|:.|::  .:.|.:.|.........:.|.:   ::|.|||.||..:.||
plant    69 AVCLSKLREYKSDLNQLKKEFKRVSSADAKPSSREELMESGMADLH---AVSADQRGRLAMSVER 130

  Fly   131 IERTGNRLTEGYRVALETEQLGAQVLNDLHHQRETLQGARARLRETNAELGRASRTLNTMMLRAL 195
            ::::.:|:.|..|:.||||::|..::.||..||:||..|..:|...:..:.::.:.|..|..|..
plant   131 LDQSSDRIRESRRLMLETEEVGISIVQDLSQQRQTLLHAHNKLHGVDDAIDKSKKVLTAMSRRMT 195

  Fly   196 REKVVLYGVGVCFVVAV 212
            |.|.::..|.|..|:|:
plant   196 RNKWIITSVIVALVLAI 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vti1a	NP_612053.1	V-SNARE	11..89	CDD:282816	20/77 (26%)
Vti1a	NP_612053.1	SNARE_Vti1a	128..189	CDD:277244	19/60 (32%)
VTI1B	NP_564255.1	V-SNARE	12..90	CDD:398604	20/77 (26%)
VTI1B	NP_564255.1	SNARE_Vti1	128..188	CDD:277215	18/59 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	50	1.000	Domainoid score	I4359
eggNOG	1	0.900	-	-		E1_KOG1666
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I2155
OMA	1	1.010	-	-		QHG54893
OrthoDB	1	1.010	-	-		D1195966at2759
OrthoFinder	1	1.000	-	-		FOG0003233
OrthoInspector	1	1.000	-	-		otm2538
orthoMCL	1	0.900	-	-		OOG6_101479
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.740