DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Vti1a and vti1a

DIOPT Version :9

Sequence 1:	NP_612053.1	Gene:	Vti1a / 38085	FlyBaseID:	FBgn0260862	Length:	230	Species:	Drosophila melanogaster
Sequence 2:	XP_005156392.1	Gene:	vti1a / 567385	ZFINID:	ZDB-GENE-050809-135	Length:	224	Species:	Danio rerio

Alignment Length:	214	Identity:	79/214 - (36%)
Similarity:	134/214 - (62%)	Gaps:	2/214 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EQYEQQYATLIAEITAHIGRLQQQNNNSERHDLCSKIDSSLPEAQELLEQMGLEVRELNPGLRSS 69
            |.|||.:.||.||||..|||:.:. ...|:..|...:|..|.|.:||:|||.|||||:....|:.
Zfish     6 EAYEQDFGTLTAEITNKIGRIPKL-AGEEKTQLVLNVDKQLEEVRELMEQMDLEVREIPIQSRAM 69

  Fly    70 FNGKLQVAQAELKRLQAEYRLTKDKQRSQANTFTTLDLGDSYEDVSIS-TDQRQRLLDNSERIER 133
            :|.:|:..:.|:::|:.:::.::.....:.......|.|.|.|...|. .::|..||||:||:||
Zfish    70 YNSRLKSYKQEMEKLEKDFKRSRIAYSDEVRNELLGDDGSSSETQLIKLREERAHLLDNTERLER 134

  Fly   134 TGNRLTEGYRVALETEQLGAQVLNDLHHQRETLQGARARLRETNAELGRASRTLNTMMLRALREK 198
            :..||..||::|:||||:|.::|.:||..||.:|.:|.|||||:|.||::||.|..|:.|.::.:
Zfish   135 SSRRLEAGYQIAVETEQVGQEILANLHSDREKIQRSRDRLRETDANLGKSSRILTGMLRRIIQNR 199

  Fly   199 VVLYGVGVCFVVAVGVSLY 217
            ::::.:|...::.:.:::|
Zfish   200 ILVFILGAIILLTIVLAIY 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vti1a	NP_612053.1	V-SNARE	11..89	CDD:282816	29/77 (38%)
Vti1a	NP_612053.1	SNARE_Vti1a	128..189	CDD:277244	32/60 (53%)
vti1a	XP_005156392.1	V-SNARE	12..90	CDD:282816	29/78 (37%)
vti1a	XP_005156392.1	SNARE_Vti1a	129..190	CDD:277244	32/60 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576430
Domainoid	1	1.000	73	1.000	Domainoid score	I9253
eggNOG	1	0.900	-	-		E1_KOG1666
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39963
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4366
OMA	1	1.010	-	-		QHG54893
OrthoDB	1	1.010	-	-		D1195966at2759
OrthoFinder	1	1.000	-	-		FOG0003233
OrthoInspector	1	1.000	-	-		oto39118
orthoMCL	1	0.900	-	-		OOG6_101479
Panther	1	1.100	-	-	LDO	PTHR21230
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1665
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800