Protein Alignment Vti1a and Gosr2

DIOPT Version :10

• Sequence 1: NP_612053.1
• Gene: Vti1a / 38085
• FlyBaseID: FBgn0260862
• Length: 230
• Species: Drosophila melanogaster
• Sequence 2: NP_062624.2
• Gene: Gosr2 / 56494
• MGIID: 1927204
• Length: 212
• Species: Mus musculus
• Alignment Length: 231
• Identity: 60/231 - (25%)
• Similarity: 104/231 - (45%)
• Gaps: 34/231 - (14%)

  Fly     4 LEQYEQQYATLIAEITAHIGRLQQQNNNSERHDLCSKIDSSLPEAQELLEQMGLEVRELNPGLRS 68
            :|...||....:.||.:|:|||::.:..|. |.:.::|.:|:.:....||:  ||:......|..
Mouse     1 MEPLYQQTNKQVQEIQSHMGRLERADKQSV-HLVENEIQASIEQIFSHLER--LEILSSKEPLNR 62

  Fly    69 SFNGKLQVAQA--ELKRLQA---------EYRLTKDKQRSQ--ANTFTTLDLGDSYEDVSISTDQ 120
            ..|.||:|.|.  :::.||.         :.|..:::||.:  :.||||.|     .|.:|..|:
Mouse    63 RQNAKLRVDQLKYDVQHLQTALRNFQHRRQVREQQERQRDELLSRTFTTND-----SDTTIPMDE 122

  Fly   121 RQRLLDNSERIERTGNRLTEGYRVALETEQLGAQVLNDLHHQRETLQGARARLRETNAELGRASR 185
            ..:...:...|....:.|..|          |..:|..|..||.||:|.:.::.:....||.::.
Mouse   123 SLQFNSSLHNIHHGMDDLIGG----------GHSILEGLRAQRLTLKGTQKKILDIANMLGLSNT 177

  Fly   186 TLNTMMLRALREKVVLYGVGVCFVVAVG--VSLYLT 219
            .:..:..||.::|..:.| |:....||.  |..|||
Mouse   178 VMRLIEKRAFQDKYFMIG-GMLLTCAVMFLVVQYLT 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vti1a	NP_612053.1	V-SNARE	11..89	CDD:461516	22/88 (25%)
		SNARE_Vti1a	128..189	CDD:277244	13/60 (22%)
Gosr2	NP_062624.2	IxM motif, signal for cargo packaging into COPII-coated vesicles. /evidence=ECO:0000250|UniProtKB:O14653	118..120		1/1 (100%)
		SNARE_GS27	120..185	CDD:277216	14/74 (19%)