Protein Alignment Vti1a and Vti1b

DIOPT Version :10

• Sequence 1: NP_612053.1
• Gene: Vti1a / 38085
• FlyBaseID: FBgn0260862
• Length: 230
• Species: Drosophila melanogaster
• Sequence 2: NP_058080.2
• Gene: Vti1b / 53612
• MGIID: 1855688
• Length: 232
• Species: Mus musculus
• Alignment Length: 223
• Identity: 56/223 - (25%)
• Similarity: 101/223 - (45%)
• Gaps: 13/223 - (5%)

  Fly     5 EQYEQQYATLIAEITAHIGRLQQQNNNSERHDLCSKIDSSLPEAQELLEQMGLEVRELNPGLRSS 69
            |:..:.:..|:.::.....||.......|:..|....|....||.|.|.:|..|:|......|:.
Mouse    12 EKLHEIFRGLLEDLQGVPERLLGTAGTEEKKKLVRDFDEKQQEANETLAEMEEELRYAPLTFRNP 76

  Fly    70 FNGKLQVAQAELKRLQAEYRLTK------DKQRSQANTFTTLDLGDSYEDVSISTDQRQRLLDNS 128
            ...||:..:.:|.:|..|.|.|.      .:...:..|:|.     ..|.::....||..||..:
Mouse    77 MMSKLRNYRKDLAKLHREVRSTPLTAAPGGRGDLKYGTYTL-----ENEHLNRLQSQRALLLQGT 136

  Fly   129 ERIERTGNRLTEGYRVALETEQLGAQVLNDLHHQRETLQGARARLRETNAELGRASRTLNTMMLR 193
            |.:.|....:...:|:|.||:|:|.:::.:|..||:.|:..::||..||..|.::.:.|.:|..:
Mouse   137 ESLNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRK 201

  Fly   194 ALREKVVLYGVGVCFVVAVGVSL-YLTF 220
            .:..|::| .|.:...:|:.|.| |..|
Mouse   202 VITNKLLL-SVIILLELAILVGLVYYKF 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vti1a	NP_612053.1	V-SNARE	11..89	CDD:461516	19/77 (25%)
		SNARE_Vti1a	128..189	CDD:277244	18/60 (30%)
Vti1b	NP_058080.2	Interaction with CLINT1. /evidence=ECO:0000250|UniProtKB:Q9UEU0	2..23		2/10 (20%)
		V-SNARE	18..96	CDD:461516	19/77 (25%)
		Interaction with CLINT1. /evidence=ECO:0000250|UniProtKB:Q9UEU0	69..73		0/3 (0%)
		SNARE_Vti1b	136..197	CDD:277243	18/60 (30%)