DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vti1a and vti-1

DIOPT Version :9

Sequence 1:	NP_612053.1	Gene:	Vti1a / 38085	FlyBaseID:	FBgn0260862	Length:	230	Species:	Drosophila melanogaster
Sequence 2:	NP_502781.1	Gene:	vti-1 / 178397	WormBaseID:	WBGene00013302	Length:	224	Species:	Caenorhabditis elegans

Alignment Length:	219	Identity:	76/219 - (34%)
Similarity:	138/219 - (63%)	Gaps:	10/219 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LEQYEQQYATLIAEITAHIGRLQQQNNNSERHDLCSKIDSSLPEAQELLEQMGLEVREL--NPGL 66
            |..:|:||:...||||:.|||:... .:|:|.....:|..||.|..:||:||.|.||||  |...
Worm    11 LSGFEKQYSLQTAEITSKIGRVHTL-PSSDRAGAVQEIRKSLEEVNDLLDQMELVVRELESNTTE 74

  Fly    67 RSSFNGKLQVAQAELKRLQAEYRLTKDKQRSQANTFTTLDLGDSYEDVSISTDQRQRLLDNSERI 131
            |:.:..:::..|::.|:|..|......:.|.:|:....|...|..::    ..|..:|:.|::|:
Worm    75 RTKYELRVRSYQSDKKQLDTELEKAIKRVREEADRDELLAFDDQLDE----HRQEDQLIANTQRL 135

  Fly   132 ERTGNRLTEGYRVALETEQLGAQVLNDLHHQRETLQGARARLRETNAELGRASRTLNTMMLRALR 196
            ||:..::.:.:|:|:||||:||::|::|..||||:..:|.|||::||:||||::||::|:.||::
Worm   136 ERSTRKVQDAHRIAVETEQIGAEMLSNLASQRETIGRSRDRLRQSNADLGRANKTLSSMIRRAIQ 200

  Fly   197 EKVVLYGVGVCFVVAVGVSLYLTF 220
            .:::|  :.|.|:::. :.||:.:
Worm   201 NRLLL--LIVTFLLSF-MFLYIVY 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vti1a	NP_612053.1	V-SNARE	11..89	CDD:282816	29/79 (37%)
Vti1a	NP_612053.1	SNARE_Vti1a	128..189	CDD:277244	29/60 (48%)
vti-1	NP_502781.1	V-SNARE	18..98	CDD:368237	29/80 (36%)
vti-1	NP_502781.1	SNARE_Vti1a	132..193	CDD:277244	29/60 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157647
Domainoid	1	1.000	71	1.000	Domainoid score	I6184
eggNOG	1	0.900	-	-		E1_KOG1666
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39963
Inparanoid	1	1.050	123	1.000	Inparanoid score	I3306
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54893
OrthoDB	1	1.010	-	-		D1195966at2759
OrthoFinder	1	1.000	-	-		FOG0003233
OrthoInspector	1	1.000	-	-		oto18175
orthoMCL	1	0.900	-	-		OOG6_101479
Panther	1	1.100	-	-	LDO	PTHR21230
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1665
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800