Protein Alignment RabX6 and RAB3D

DIOPT Version :10

• Sequence 1: NP_001261219.1
• Gene: RabX6 / 38084
• FlyBaseID: FBgn0035155
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_004274.1
• Gene: RAB3D / 9545
• HGNCID: 9779
• Length: 219
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 67/219 - (30%)
• Similarity: 111/219 - (50%)
• Gaps: 38/219 - (17%)

  Fly    10 KVILCGDYGVGKSSLFRRFATNTFITDTDRKSTLGLDHIDREYSVNEKQIKLQLWDTGGMERVAS 74
            |::|.|:..|||:|...|:|.::|....  .||:|:|...:....::|:||||:|||.|.||..:
Human    24 KLLLIGNSSVGKTSFLFRYADDSFTPAF--VSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRT 86

  Fly    75 VTSSYYKFAEGAILVFALDNAASFHSLSQHLLDIVTYA-ENAKIFICGNKSDL---------DGR 129
            :|::||:.|.|.:|::.:.|..||.::......|.||: :||::.:.|||.||         |||
Human    87 ITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGR 151

  Fly   130 EPEVSDEEVEAFCEQCHSLISATYKTSCRSGAGVEEMFRDISRQLVHANRSKMELQALEHKSFQV 194
              .::|:....|           ::.|.:....|:::|    .:||.....||. ::||..|
Human   152 --RLADDLGFEF-----------FEASAKENINVKQVF----ERLVDVICEKMN-ESLEPSS--- 195

  Fly   195 DTASSGAATNEEDA-----SSCGC 213
            .:.|:|......||     |||.|
Human   196 SSGSNGKGPAVGDAPAPQPSSCSC 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	52/171 (30%)
RAB3D	NP_004274.1	Rab3	22..186	CDD:206657	54/180 (30%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		3/10 (30%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		6/15 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..219		10/31 (32%)