DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX6 and RRAD

DIOPT Version :9

Sequence 1:	NP_001261219.1	Gene:	RabX6 / 38084	FlyBaseID:	FBgn0035155	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001122322.1	Gene:	RRAD / 6236	HGNCID:	10446	Length:	308	Species:	Homo sapiens

Alignment Length:	180	Identity:	46/180 - (25%)
Similarity:	78/180 - (43%)	Gaps:	13/180 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KVILCGDYGVGKSSLFRRFATNTFITDTDRKSTLGLDHIDREYSVNEKQIKLQLWDTGGMERVAS 74
            ||:|.|..|||||:|.|.|..   :.|.......|..: ||...|:.::..|.::|....:....
Human    93 KVLLLGAPGVGKSALARIFGG---VEDGPEAEAAGHTY-DRSIVVDGEEASLMVYDIWEQDGGRW 153

  Fly    75 VTSSYYKFAEGAILVFALDNAASFHSLSQHLLDI--VTYAENAKIFICGNKSDLDGREPEVSDEE 137
            :........:..::|:::.:..||...|:..:.:  ....::..|.:.|||||| .|..|||.:|
Human   154 LPGHCMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDL-VRSREVSVDE 217

  Fly   138 VEAFCEQCHSLISATY-KTSCRSGAGVEEMFRDISRQLVHANRSKMELQA 186
            ..|    |..:....: :||......|:.:|..:.|| :...|...|..|
Human   218 GRA----CAVVFDCKFIETSAALHHNVQALFEGVVRQ-IRLRRDSKEANA 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX6	NP_001261219.1	RAB	10..176	CDD:197555	43/168 (26%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	41/164 (25%)
RRAD	NP_001122322.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..88
		RGK	92..308	CDD:206715	46/180 (26%)
		RAS	92..252	CDD:214541	43/168 (26%)
		Calmodulin-binding	278..297
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910