Protein Alignment RabX6 and RAB3A

DIOPT Version :10

• Sequence 1: NP_001261219.1
• Gene: RabX6 / 38084
• FlyBaseID: FBgn0035155
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_002857.1
• Gene: RAB3A / 5864
• HGNCID: 9777
• Length: 220
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 62/208 - (29%)
• Similarity: 107/208 - (51%)
• Gaps: 15/208 - (7%)

  Fly    10 KVILCGDYGVGKSSLFRRFATNTFITDTDRKSTLGLDHIDREYSVNEKQIKLQLWDTGGMERVAS 74
            |:::.|:..|||:|...|:|.::|....  .||:|:|...:....|:|:||||:|||.|.||..:
Human    24 KILIIGNSSVGKTSFLFRYADDSFTPAF--VSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRT 86

  Fly    75 VTSSYYKFAEGAILVFALDNAASFHSLSQHLLDIVTYA-ENAKIFICGNKSDLDGREPEVSDEEV 138
            :|::||:.|.|.||::.:.|..||:::......|.||: :||::.:.|||.|::. |..||.|..
Human    87 ITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMED-ERVVSSERG 150

  Fly   139 EAFCEQCHSLISATYKTSCRSGAGVEEMFRDISRQLVHANRSKMELQALEHKSFQVDTASSGAAT 203
            ....:.   |....::.|.:....|::.|    .:||.....||. ::|:.....|..|..|...
Human   151 RQLADH---LGFEFFEASAKDNINVKQTF----ERLVDVICEKMS-ESLDTADPAVTGAKQGPQL 207

  Fly   204 NEEDA---SSCGC 213
            :::..   ..|.|
Human   208 SDQQVPPHQDCAC 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	52/162 (32%)
RAB3A	NP_002857.1	Rab3	22..186	CDD:206657	54/171 (32%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		3/10 (30%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		6/15 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..220		4/25 (16%)