DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX6 and RRAGD

DIOPT Version :9

Sequence 1:	NP_001261219.1	Gene:	RabX6 / 38084	FlyBaseID:	FBgn0035155	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_067067.1	Gene:	RRAGD / 58528	HGNCID:	19903	Length:	400	Species:	Homo sapiens

Alignment Length:	275	Identity:	56/275 - (20%)
Similarity:	95/275 - (34%)	Gaps:	77/275 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KQKVILCGDYGVGKSSL----FRRFATN--TFITDTDRKSTLGLDHIDREYSVNEKQIKLQLWDT 66
            |.:::|.|....||||:    |.:.:.|  .|:..|::        |.||...|...:..|:||.
Human    62 KPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNK--------ICREDVSNSSFVNFQIWDF 118

  Fly    67 GGMERVASVTSSYYKFAEG-AILVFALDNAASFHSLSQHLLDIVTYAE------NAKIFICGNKS 124
            .|.......|..|.....| ..|:|.:|:...:......|...||.|.      |.::||    .
Human   119 PGQIDFFDPTFDYEMIFRGTGALIFVIDSQDDYMEALARLHLTVTRAYKVNTDINFEVFI----H 179

  Fly   125 DLDGREPE------------VSDEEVEAFCEQC-----------HSLISATYKTSCR-------- 158
            .:||...:            .:|:..:|..|:.           ||:..|..|...:
Human   180 KVDGLSDDHKIETQRDIHQRANDDLADAGLEKIHLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTL 244

  Fly   159 --------SGAGVEE--MFRDISRQLVHANRSKMELQALEHKSFQVDTA----------SSGAAT 203
                    |.:|:|:  :|..:|:..:..:.:.:::|..|.....:|..          ..||.|
Human   245 ENLLNIFISNSGIEKAFLFDVVSKIYIATDSTPVDMQTYELCCDMIDVVIDISCIYGLKEDGAGT 309

  Fly   204 NEEDASSCGCXQLGN 218
             ..|..|... :|.|
Human   310 -PYDKESTAIIKLNN 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX6	NP_001261219.1	RAB	10..176	CDD:197555	45/219 (21%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	44/215 (20%)
RRAGD	NP_067067.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..54
RRAGD	NP_067067.1	RagC_like	64..238	CDD:206745	40/185 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910