DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX6 and Rragd

DIOPT Version :9

Sequence 1:	NP_001261219.1	Gene:	RabX6 / 38084	FlyBaseID:	FBgn0035155	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001355984.1	Gene:	Rragd / 52187	MGIID:	1098604	Length:	454	Species:	Mus musculus

Alignment Length:	228	Identity:	51/228 - (22%)
Similarity:	84/228 - (36%)	Gaps:	59/228 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KQKVILCGDYGVGKSSL----FRRFATN--TFITDTDRKSTLGLDHIDREYSVNEKQIKLQLWDT 66
            |.:::|.|....||||:    |.:.:.:  .|:..|:|        |.||...|...:..|:||.
Mouse   116 KPRILLMGLRRSGKSSIQKVVFHKMSPSETLFLESTNR--------ICREDVSNSSFVNFQIWDF 172

  Fly    67 GGMERVASVTSSYYKFAEG-AILVFALDNAASFHSLSQHLLDIVTYAE------NAKIFICGNKS 124
            .|.......|..|.....| ..|:|.:|:...:......|...||.|.      |.::||    .
Mouse   173 PGQIDFFDPTFDYEMIFRGTGALIFVIDSQDDYMEALARLHLTVTRAYKVNTDINFEVFI----H 233

  Fly   125 DLDGREPE------------VSDEEVEAFCEQCHSLISATYKTSCRSGAGVEEMFRDISRQLVHA 177
            .:||...:            .:|:..:|..|:.|   .:.|.||....: :.|.|..:.::|:
Mouse   234 KVDGLSDDHKIETQRDIHQRANDDLADAGLEKIH---LSFYLTSIYDHS-IFEAFSKVVQKLI-- 292

  Fly   178 NRSKMELQALEH------------KSFQVDTAS 198
                .:|..||:            |:|..|..|
Mouse   293 ----PQLPTLENLLNIFISNSGIEKAFLFDVVS 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX6	NP_001261219.1	RAB	10..176	CDD:197555	43/190 (23%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	42/186 (23%)
Rragd	NP_001355984.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55
		RagC_like	118..292	CDD:206745	42/189 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	433..454
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910