DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX6 and ran

DIOPT Version :9

Sequence 1:	NP_001261219.1	Gene:	RabX6 / 38084	FlyBaseID:	FBgn0035155	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001004829.1	Gene:	ran / 448091	XenbaseID:	XB-GENE-489468	Length:	216	Species:	Xenopus tropicalis

Alignment Length:	202	Identity:	58/202 - (28%)
Similarity:	97/202 - (48%)	Gaps:	17/202 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KVILCGDYGVGKSSLFRRFATNTFITDTDRK--STLGLDHIDREYSVNEKQIKLQLWDTGGMERV 72
            |::|.||.|.||::..:|..|..|    ::|  :|||::.....:..|...||..:|||.|.|:.
Frog    12 KLVLVGDGGTGKTTFVKRHLTGEF----EKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKF 72

  Fly    73 ASVTSSYYKFAEGAILVFALDNAASFHSLSQHLLDIVTYAENAKIFICGNKSDLDGREPEVSDEE 137
            ..:...||..|:.||::|.:.:..::.::.....|:|...||..|.:||||.|       :.|.:
Frog    73 GGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVD-------IKDRK 130

  Fly   138 VEAFCEQCHSLISAT-YKTSCRSGAGVEEMFRDISRQLV-HANRSKMELQALEHKSFQVDTASSG 200
            |:|.....|...:.. |..|.:|....|:.|..::|:|: ..|...:.:.||......:|.|.
Frog   131 VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNFEFVAMPALAPPEVVMDPAL-- 193

  Fly   201 AATNEED 207
            ||..|:|
Frog   194 AAQYEQD 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX6	NP_001261219.1	RAB	10..176	CDD:197555	49/169 (29%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	47/164 (29%)
ran	NP_001004829.1	PTZ00132	1..216	CDD:240284	58/202 (29%)
ran	NP_001004829.1	Interaction with RANBP1. /evidence=ECO:0000250\|UniProtKB:P62826	211..216
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910