DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX6 and CenG1A

DIOPT Version :9

Sequence 1:	NP_001261219.1	Gene:	RabX6 / 38084	FlyBaseID:	FBgn0035155	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_723849.1	Gene:	CenG1A / 34803	FlyBaseID:	FBgn0028509	Length:	995	Species:	Drosophila melanogaster

Alignment Length:	176	Identity:	34/176 - (19%)
Similarity:	80/176 - (45%)	Gaps:	20/176 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IPKQKVILCGDYGVGKSSLFRRFATNTFITDTDRKSTLGLDHIDREYSVNEKQIKLQLWDTGGME 70
            :|..::.:.|....|||:|..|:.|.:::.:...:.    ....:|..::.:...|.:.|.||..
  Fly   140 VPDLRLGIVGSLNSGKSALVHRYLTGSYMQEESPEG----GRFKKEVFIDGQSYLLLIRDEGGAP 200

  Fly    71 RVASVTSSYYKFAEGAILVFALDNAASFHSLSQHLLDIVTYAENAKI--FICGNKSDLDGREPEV 133
            .:     .:..:.:..|.||:|:|..||:::..:...:..:....:|  .:.|.:..:..|.|.|
  Fly   201 EM-----QFAGWVDAVIFVFSLENEGSFNTVYNYYTKMAHFRNGQEIPMILVGTQDAISERNPRV 260

  Fly   134 SDE----EVEAFCEQCHSLISATYKTSCRSGAGVEEMFRDISRQLV 175
            .|:    ::.:..::|     :.|:|....|..||.:|:|..::::
  Fly   261 IDDTRARKLASDLKRC-----SYYETCATYGLNVERVFQDACQKIL 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX6	NP_001261219.1	RAB	10..176	CDD:197555	33/172 (19%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	33/167 (20%)
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453
		Centaurin_gamma	143..300	CDD:133303	33/170 (19%)
		RAS	144..295	CDD:214541	32/164 (20%)
		PH_AGAP	451..686	CDD:241281
		PH	454..>521	CDD:278594
		ArfGap	702..818	CDD:279720
		ANK	<834..907	CDD:238125
		ANK repeat	834..866	CDD:293786
		Ank_5	859..907	CDD:290568
		ANK repeat	868..897	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2762
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.950