DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RabX6 and Dnajc27

DIOPT Version :9

Sequence 1:	NP_001261219.1	Gene:	RabX6 / 38084	FlyBaseID:	FBgn0035155	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_996727.2	Gene:	Dnajc27 / 298859	RGDID:	1564414	Length:	273	Species:	Rattus norvegicus

Alignment Length:	222	Identity:	56/222 - (25%)
Similarity:	99/222 - (44%)	Gaps:	35/222 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IPKQ---------KVILCGDYGVGKSSLFRRFATNTFITDTDRKSTLGLDHIDREYSVNEKQIKL 61
            :||:         |||..|:..||||.:.:|:....|:  :...:|:|:|:...:..|.:::||:
  Rat     5 VPKRKEPLKSLRIKVISMGNAEVGKSCIIKRYCEKRFV--SKYLATIGIDYGVTKVQVRDREIKV 67

  Fly    62 QLWDTGGMERVASVTSSYYKFAEGAILVFALDNAASFHSLSQHLLDIVT------YAENAKIFIC 120
            .::|..|......|.:.:||..:|.|||:.:....||.:|...|.::..      ..||....:|
  Rat    68 NIFDMAGHPFFFEVRNEFYKDTQGVILVYDVGQKDSFDALDSWLAEMKQELGPHGNMENIVFVVC 132

  Fly   121 GNKSDLDGREPEVSDEEVEAFCEQCHSLISATYKTSCRSGAGVEEMFRDISRQLVH--ANRSKME 183
            .||.|. .:...:.:.|...:.|....|.   ::||.::|.|:.|||:.....:|.  .|..|.
  Rat   133 ANKIDC-SKHRCIDESEGRLWAESRGFLY---FETSAQTGEGINEMFQTFYMSIVDLCENGGKR- 192

  Fly   184 LQALEHKSFQVDTASSGAATNEEDASS 210
                       .||:|.|:..:|.|.:
  Rat   193 -----------PTANSSASYTKEQADT 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX6	NP_001261219.1	RAB	10..176	CDD:197555	45/171 (26%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	45/167 (27%)
Dnajc27	NP_996727.2	Required for interaction with MAPK1. /evidence=ECO:0000250\|UniProtKB:Q8CFP6	1..18		2/12 (17%)
		RJL	17..184	CDD:133319	45/172 (26%)
		DnaJ	217..264	CDD:99751
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0098
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900