DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX6 and Rab12

DIOPT Version :9

Sequence 1:	NP_001261219.1	Gene:	RabX6 / 38084	FlyBaseID:	FBgn0035155	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_037149.1	Gene:	Rab12 / 25530	RGDID:	3527	Length:	243	Species:	Rattus norvegicus

Alignment Length:	181	Identity:	65/181 - (35%)
Similarity:	101/181 - (55%)	Gaps:	10/181 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KQKVILCGDYGVGKSSLFRRFATNTFITDTDRKSTLGLDHIDREYSVNEKQIKLQLWDTGGMERV 72
            |.:||:.|..||||:||..||..:||....  |||:|:|...:...:..|:|:||:|||.|.||.
  Rat    41 KLQVIIIGSRGVGKTSLMERFTDDTFCEAC--KSTVGVDFKIKTVELRGKKIRLQIWDTAGQERF 103

  Fly    73 ASVTSSYYKFAEGAILVFALDNAASFHSLSQHLLDIVTYA-ENAKIFICGNKSDLDGREPEVSDE 136
            .|:||:||:.|:|.|||:.:....:|..|.:.:..|..|| |:|::.:.|||.|.: .:.|:|.:
  Rat   104 NSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCE-TDREISRQ 167

  Fly   137 EVEAFCEQCHSLISATYKTSCRSGAGVEEMFRDISRQLVHANRSKMELQAL 187
            :.|.|.:|...:  ...:.|.:....|:|:|    .:||.....||.|..|
  Rat   168 QGEKFAQQITGM--RFCEASAKDNFNVDEIF----LKLVDDILKKMPLDVL 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX6	NP_001261219.1	RAB	10..176	CDD:197555	59/166 (36%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	58/162 (36%)
Rab12	NP_037149.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36
		Rab12	42..243	CDD:206699	64/180 (36%)
		Effector region. /evidence=ECO:0000250	70..78		4/9 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910