DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX6 and Dnajc27

DIOPT Version :9

Sequence 1:	NP_001261219.1	Gene:	RabX6 / 38084	FlyBaseID:	FBgn0035155	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	XP_006515115.1	Gene:	Dnajc27 / 217378	MGIID:	2443036	Length:	298	Species:	Mus musculus

Alignment Length:	247	Identity:	60/247 - (24%)
Similarity:	103/247 - (41%)	Gaps:	60/247 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IPKQ---------KVILCGDYGVGKSSLFRRFATNTFITDTDRKSTLGLDHIDREYSVNEKQIKL 61
            :||:         |||..|:..||||.:.:|:....|:  :...:|:|:|:...:..|.:::||:
Mouse     5 VPKRKEPAKSLRIKVISMGNAEVGKSCIIKRYCEKRFV--SKYLATIGIDYGVTKVQVRDREIKV 67

  Fly    62 QLWDTGGMERVASVTSSYYKFAEGAILVFALDNAASFHSLSQHLLDIVT------YAENAKIFIC 120
            .::|..|......|.:.:||..:|.|||:.:....||.:|...|.::..      ..:|....:|
Mouse    68 NIFDMAGHPFFFEVRNEFYKDTQGVILVYDVGQKDSFDALDSWLAEMKQELGPHGNMDNIVFVVC 132

  Fly   121 GNKSDLDGRE---PEVSDEEVEAFCE-------QC--HSLISAT-------------YKTSCRSG 160
            .||    ||:   |.|..:...:.|.       .|  |..|..:             ::||.::|
Mouse   133 ANK----GRDLTWPGVVGQGGFSLCPALTLFQIDCSKHRCIDESEGRLWAESKGFLYFETSAQTG 193

  Fly   161 AGVEEMFRDISRQLVH--ANRSKMELQALEHKSFQVDTASSGAATNEEDASS 210
            .|:.|||:.....:|.  .|..|.            .||||.|:..:|.|.:
Mouse   194 EGINEMFQTFYLSIVDLCENGGKR------------PTASSSASFTKEQADT 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX6	NP_001261219.1	RAB	10..176	CDD:197555	48/196 (24%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	48/192 (25%)
Dnajc27	XP_006515115.1	RJL	17..209	CDD:133319	48/197 (24%)
Dnajc27	XP_006515115.1	DnaJ	242..289	CDD:99751
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0098
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900