DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment RabX6 and Rap1b

DIOPT Version :9

Sequence 1:NP_001261219.1 Gene:RabX6 / 38084 FlyBaseID:FBgn0035155 Length:222 Species:Drosophila melanogaster
Sequence 2:NP_077777.1 Gene:Rap1b / 215449 MGIID:894315 Length:184 Species:Mus musculus


Alignment Length:167 Identity:47/167 - (28%)
Similarity:85/167 - (50%) Gaps:8/167 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 KVILCGDYGVGKSSLFRRFATNTFITDTDRKSTLGLDHIDREYSVNEKQIKLQLWDTGGMERVAS 74
            |:::.|..|||||:|..:|....|:...|  .|:. |...::..|:.:|..|::.||.|.|:..:
Mouse     5 KLVVLGSGGVGKSALTVQFVQGIFVEKYD--PTIE-DSYRKQVEVDAQQCMLEILDTAGTEQFTA 66

  Fly    75 VTSSYYKFAEGAILVFALDNAASFHSLSQHLLDI--VTYAENAKIFICGNKSDLDGREPEVSDEE 137
            :...|.|..:|..||:::...::|:.|......|  |...::..:.:.|||.||:. |..|..|:
Mouse    67 MRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLED-ERVVGKEQ 130

  Fly   138 VEAFCEQCHSLISATYKTSCRSGAGVEEMFRDISRQL 174
            .:....|.::  .|..::|.:|...|.|:|.|:.||:
Mouse   131 GQNLARQWNN--CAFLESSAKSKINVNEIFYDLVRQI 165

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RabX6NP_001261219.1 RAB 10..176 CDD:197555 47/167 (28%)
Rab 10..172 CDD:206640 45/163 (28%)
Rap1bNP_077777.1 Rap1 3..167 CDD:133375 47/167 (28%)
Interaction with KRIT1. /evidence=ECO:0000250 25..67 11/44 (25%)
Effector region. /evidence=ECO:0000305 32..40 3/10 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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