Protein Alignment hiro and KEX1

DIOPT Version :10

• Sequence 1: NP_612051.1
• Gene: hiro / 38083
• FlyBaseID: FBgn0035154
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_011312.1
• Gene: KEX1 / 852670
• SGDID: S000003171
• Length: 729
• Species: Saccharomyces cerevisiae
• Alignment Length: 469
• Identity: 110/469 - (23%)
• Similarity: 190/469 - (40%)
• Gaps: 99/469 - (21%)

  Fly    14 GFAGLASVDARKGYGPGDQDWGFVDVRTGAHMFYWLYYTTANVSSYTERPLAIWLQGGPGASSTG 78
            |...|.|.||      .:||      .:....|:| .:|..:.:...:|||.|||.||||.||..
Yeast    54 GHIPLRSEDA------DEQD------SSDLEYFFW-KFTNNDSNGNVDRPLIIWLNGGPGCSSMD 105

  Fly    79 YGNFEELGPLKL--DGS--YRDWTWVKDMNVMFIDNPVGSGFSYVDGSSYYTTNNKQIALDL--- 136
             |...|.||.::  ||.  ..:.:|:...:::|||.|.|:|||..........:..:...||
Yeast   106 -GALVESGPFRVNSDGKLYLNEGSWISKGDLLFIDQPTGTGFSVEQNKDEGKIDKNKFDEDLEDV 169

  Fly   137 ----VELMKGFYTNHPEFKTVPLHIFCESYGGKMAPEFALELDYAIKRGEIES---NFVSVALGD 194
                ::.::.::...||..|..:.:..|||.|:..|.||..:....|..:|:.   :..::.:|:
Yeast   170 TKHFMDFLENYFKIFPEDLTRKIILSGESYAGQYIPFFANAILNHNKFSKIDGDTYDLKALLIGN 234

  Fly   195 PWTSPIDSVLSWAPFLLQLGIVDQ---------DGHDKIE--ASALKTKD-----YVDREKWTQA 243
            .|..|....||:.||.::..::|:         :.|:..:  .::..|.:     |.:.|.....
Yeast   235 GWIDPNTQSLSYLPFAMEKKLIDESNPNFKHLTNAHENCQNLINSASTDEAAHFSYQECENILNL 299

  Fly   244 TLQWSSTQSVVLRES--KG-VDFYNVETPTLGDQYRLMSRAAMTPEEVMYRTLVKF--------D 297
            .|.::       |||  || .|..|:....|.|.|  .|.....|:::.:  :.||        .
Yeast   300 LLSYT-------RESSQKGTADCLNMYNFNLKDSY--PSCGMNWPKDISF--VSKFFSTPGVIDS 353

  Fly   298 VDEDRDKLLEDLMLGPVTEALGINTGVKWGAQSGTTFTKLMGDFMKPAVDVVGELLNNTTVKVGV 362
            :..|.||:                  ..|...:.:..|||.....||::.::..|| .:.:::.:
Yeast   354 LHLDSDKI------------------DHWKECTNSVGTKLSNPISKPSIHLLPGLL-ESGIEIVL 399

  Fly   363 FSGGLDLICATPGAVNWIEAMEWSAKPSYQVSPRVGITVDRV-----------LEGYEKTYGNFS 416
            |:|..||||...|.::.|:.::|.....:...   .::.|.:           ..||.|...|.:
Yeast   400 FNGDKDLICNNKGVLDTIDNLKWGGIKGFSDD---AVSFDWIHKSKSTDDSEEFSGYVKYDRNLT 461

  Fly   417 MFWVNRAGHMVPAD 430
            ...|..|.||||.|
Yeast   462 FVSVYNASHMVPFD 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hiro	NP_612051.1	Peptidase_S10	32..444	CDD:459815	105/451 (23%)
KEX1	NP_011312.1	Peptidase_S10	37..484	CDD:459815	110/469 (23%)