DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment hiro and sxa2

DIOPT Version :9

Sequence 1:	NP_612051.1	Gene:	hiro / 38083	FlyBaseID:	FBgn0035154	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_593043.1	Gene:	sxa2 / 2541701	PomBaseID:	SPAC1296.03c	Length:	507	Species:	Schizosaccharomyces pombe

Alignment Length:	462	Identity:	107/462 - (23%)
Similarity:	173/462 - (37%)	Gaps:	108/462 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 GFVDVRTGAHMFYWLYYTTANVSSYTERPLAIWLQGGPGASSTGYGNFEELGPLKL-----DGSY 94
            |:::..:...:||  .|..|.|.|.|   ..:|||||||.:.| .|.|.|.||:::     ..|.
pombe    77 GYLEANSDKSLFY--TYAPAVVDSET---FIVWLQGGPGCAGT-LGFFSENGPIEISQSSPSPSL 135

  Fly    95 RDWTWVKDMNVMFIDNPVGSGFSYVDGSSYYTTNNKQIALDLVELMKGFYTNHPEFKTVPLHIFC 159
            ...:|....|::::|.|.|:|:|  .|.:.|||..::.:.|.|..:|.||...|......|::..
pombe   136 NPESWTNFANMLWLDQPFGTGYS--QGQAAYTTTIEEASSDFVNALKSFYQKFPHLMKKKLYLVG 198

  Fly   160 ESYGGKMAPEFALELDYAIKRGEIESNFVSVALGDPWTSPID-----SVLSWAPFLLQLGIVDQD 219
            ||||...:..||..|   :....:..||:.|.:....|:..:     :...|...:.:||....:
pombe   199 ESYGSIWSANFAEAL---LSEPSLNINFMGVGIVSGLTADYETQEQITASIWVEHISKLGYYFNN 260

  Fly   220 GHDKIEASALKTKDYVDREKWTQ-----ATLQWSSTQSVVLRESKGVDFYNVETPTLGDQYRLMS 279
                  .|:..::::..|.|..|     ..|.:.:.|..:.|..     ||..|.|     .|..
pombe   261 ------TSSTISEEFKKRNKECQYDSVLNRLTFPTEQYPIWRPE-----YNFSTST-----SLRK 309

  Fly   280 RAAMTPEEV-------------------MY---RTLVKFDVDED---------------RDKLLE 307
            |.|:..|::                   :|   ..::.:||..|               |:.:..
pombe   310 REALDGEDIGNVFNSISGCDLYSLSNFLLYLENSCVITYDVSLDCSFNEYNDPLITYLNREDVRS 374

  Fly   308 DLMLGPVTEALGINTGVKWGAQSGTTFTKLMGDFMKPAV-----DVVGELLNNTT--VKVGVFSG 365
            .|.....:.||....||   ...|..|     |..|..|     .|:.|::...|  .||...:|
pombe   375 SLHATKASTALTSGEGV---FADGCNF-----DLYKKIVSNNVESVLVEIIPRLTEKYKVSFLAG 431

  Fly   366 GLDLICATPGAVNWIEAMEWSAKPSYQVSP-----RVGITVDRVLEGYEKTYGNFSMFWVNRAGH 425
            .|||.....|.:..::...|:....:..||     ..|.|:|.         .|.:....|..||
pombe   432 ALDLQILWTGTLLALQNTTWNGWQGFTQSPGSLETTNGFTLDE---------RNLAFTLSNSVGH 487

  Fly   426 MVPADNP 432
            |.|:.:|
pombe   488 MAPSKDP 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hiro	NP_612051.1	Peptidase_S10	29..444	CDD:298660	107/462 (23%)
sxa2	NP_593043.1	Kex1	1..507	CDD:225490	107/462 (23%)
sxa2	NP_593043.1	Peptidase_S10	65..503	CDD:298660	107/462 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I1757
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11802
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050