DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hiro and F22E12.1

DIOPT Version :9

Sequence 1:	NP_612051.1	Gene:	hiro / 38083	FlyBaseID:	FBgn0035154	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_505684.2	Gene:	F22E12.1 / 179460	WormBaseID:	WBGene00009058	Length:	763	Species:	Caenorhabditis elegans

Alignment Length:	204	Identity:	42/204 - (20%)
Similarity:	68/204 - (33%)	Gaps:	61/204 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 WLQGGPGASSTGY---------GNFEELGPLKLDGSYRDWTWVKDMN-------VMFIDNPVGSG 115
            |..|..|.|:..|         |.:.|.|| .:|..|    |.:.||       :...:||..|.
Worm   116 WWSGCGGNSNIYYSYNHCMLICGEYAEHGP-GIDEKY----WGRQMNRSMSAESLHVFNNPTESF 175

  Fly   116 FSYVD---------GSSYYTT-----------NNKQIALDLVELMKG-FYTNHPEFKTVPLHIFC 159
            ..|.:         .:|||.:           :||.:.:::.....| .|.:.....|||:.
Worm   176 HQYSEEPYPVQVPLENSYYDSHPRRYGNSDNWDNKLMTINISHRDDGPSYFHAAPAVTVPMF--- 237

  Fly   160 ESYGGKMAPEFALELD-YAIKRGEIESNFVSVALGDPWTSPIDSVLSWAPFLLQLGIVDQDGHDK 223
                .:.|..|..:.| ..|.|.:.|...:.|         :|..::|.  :.:.....|:|..|
Worm   238 ----SRAAQSFKTQADGLTIHRYDSEPRPMQV---------LDQDVNWQ--IQEQASAQQNGFMK 287

  Fly   224 IEASALKTK 232
            ......|.|
Worm   288 RRFKMQKKK 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hiro	NP_612051.1	Peptidase_S10	29..444	CDD:298660	42/204 (21%)
F22E12.1	NP_505684.2	KU	25..76	CDD:238057
F22E12.1	NP_505684.2	KU	85..138	CDD:238057	5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165187
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930