DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ebd1 and CG13894

DIOPT Version :9

Sequence 1:	NP_612050.1	Gene:	ebd1 / 38082	FlyBaseID:	FBgn0035153	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_612054.1	Gene:	CG13894 / 38086	FlyBaseID:	FBgn0035157	Length:	528	Species:	Drosophila melanogaster

Alignment Length:	521	Identity:	111/521 - (21%)
Similarity:	187/521 - (35%)	Gaps:	151/521 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 PDQIKRIVQQRAEILNAWDQRTRRSQDAKTMETKTVRVSMLGKAVYDWIRRMMYYKDF--SISDG 186
            |..::.:.||      |..:...||:          :.:.:...||:|:.|.......  ||:.|
  Fly    85 PSNLEAVEQQ------AMVEEIERSR----------KCAYINAVVYEWLVRANINPQLRGSITHG 133

  Fly   187 LIQKMALQFKSSMNLAHFFPHQEWCDKFRRTYSIQHSDTRLLKIGYTQ----GYSVQIKDIVKDV 247
            :|:..|...:..:....|.....|.::||.|    |......|:...|    |.|:.|.|||:|:
  Fly   134 MIKDKAENARQVIGSTSFIADNRWLNRFRET----HLQGFAQKLASNQLKPLGSSLWIPDIVQDL 194

  Fly   248 MSESMPESGPRNGEEDDEEVSLGSPVSSHPRSYV---------EDEDDEVDVDGGGISGEDDLEE 303
            .....|.|..|..:           :...|..|:         |::||.:||.      |...:|
  Fly   195 AHLFPPASAERVAK-----------LEEMPEQYMTYMQQYGEYEEDDDSMDVK------EQSYQE 242

  Fly   304 EPDVKPSLSELNFARALK-----------PLPPLVRLPLQANTPPGTTQKVLLATPIVPTQAGG- 356
            :...:    :.:||...:           |.||.          ||        .|..||...|
  Fly   243 QQQQQ----QQHFALQQQHMQQQQHQMGHPWPPF----------PG--------HPGHPTPHPGF 285

  Fly   357 ------------QPMTMTIIPLATLAQSITKIPAPQQQDKGPVVP---PPKLEIKQEKEIKVEPK 406
                        |.|...:.....:.|....:| ||::...|.:|   ||:         :..|.
  Fly   286 ASFNDFYFERHQQQMQQQLQQQQQMQQFPPTMP-PQREPFQPQLPPNVPPQ---------RASPF 340

  Fly   407 DPEELLAKQPEAELQENDDRAQREKDLEIPPTVHIKVEPEAE--LESELDQDPADLDEDANN--G 467
            .|.: |||:|:.|..::|:..:....:..||      .|.||  |.|:..:..:..:::.||  |
  Fly   341 QPVQ-LAKRPKMESPDDDEVQEINSAVNSPP------YPLAESTLTSKHSRSSSPNEQNNNNSGG 398

  Fly   468 RSSVTS-------------LAEVLAANVEDEMEYIEQMRQRKVSSPAAVENSLNPRQGTKRRYES 519
            |.|.:|             ....|::..:|..........:..|:||:.:...|.        .|
  Fly   399 RDSASSKENAPKGGGTSGKSTPALSSKGKDSPAPARAASTKPASAPASPKKIPNG--------SS 455

  Fly   520 AQDDNNNGGSGQESGSSVISCA--------DARKYLKLLEEFALYKENYRLIELITRADEVMREM 576
            :.....||.:..:.......|.        .|.:|||.||:|.|:|||:|.|.|:::.:.|:|:.
  Fly   456 SSGSQTNGHTSPDPEDKKALCMLKELESYHQALEYLKPLEDFVLFKENFRAIGLLSQLELVLRKG 520

  Fly   577 D 577
            |
  Fly   521 D 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ebd1	NP_612050.1	HTH	90..138	CDD:304362	3/13 (23%)
ebd1	NP_612050.1	CENPB	158..224	CDD:197828	15/67 (22%)
CG13894	NP_612054.1	THAP	6..82	CDD:214951
		CENPB	104..165	CDD:197828	14/74 (19%)
		NST1	382..>468	CDD:290656	15/93 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2F66R
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0014353
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.900