Protein Alignment Rev1 and poli

DIOPT Version :10

• Sequence 1: NP_612047.1
• Gene: Rev1 / 38079
• FlyBaseID: FBgn0035150
• Length: 995
• Species: Drosophila melanogaster
• Sequence 2: NP_001017834.1
• Gene: poli / 550532
• ZFINID: ZDB-GENE-050417-376
• Length: 710
• Species: Danio rerio
• Alignment Length: 799
• Identity: 171/799 - (21%)
• Similarity: 291/799 - (36%)
• Gaps: 251/799 - (31%)

  Fly   272 ERYVMHIDMDCFFVSVGLRTRPELRGLPIAVTHSKGGNAATDVPVHPQADRKAELELFAQRFEHH 336
            :|.::|.|:|||:..|.:...|.||..|:.:                           .|::
Zfish    36 QRVILHFDLDCFYAQVEMIRNPALRTKPLGI---------------------------QQKY--- 70

  Fly   337 FHDGDKAEKVRSGFDKKMSLSEIASCSYEAREKGIRNGMFVGQALKLCPELKTIP-YDFEGYKEV 400
                                 .|.:.:|.|||.|:...|.|..|::.||:|..:. .|...|:|:
Zfish    71 ---------------------IIVTSNYVARELGVNKLMSVTDAVEKCPQLVLVKGEDLTHYREM 114

  Fly   401 AFTLYDTVAQYTLNIEAVSCDEMFVELTDLAH----ELNVDVMAFVSH----------------- 444
            ::.:.:.:..|...:|.:..||.|:::|::..    |..:..::|..|
Zfish   115 SYKVTELLMSYCPLVERLGFDENFMDVTEMVEKRIKETRISDLSFNGHVYNHESVVVDEENIRLA 179

  Fly   445 --------LRQEVYSKTGCPCSAGVAGNKLLARMATKEAKPNGQ-FLLDSSN-DILAYMAPMSLD 499
                    :||.::|..|....||||.|||||::.:...|||.| .||..|| ::::.:.  .|.
Zfish   180 VGSVIAAEMRQAIFSTLGLTGCAGVASNKLLAKLVSGSFKPNQQTTLLPHSNAELMSSLT--GLI 242

  Fly   500 LLPGVGSSISHKLKQAGLNNCGDVQNTTLEKMEKVLGK---KLGQNLFQNCRGIDDRPLAYEQIR 561
            .:||:|.....|||..||.|..|:|...|..:.|..|:   |..|||  .| ||||.|:......
Zfish   243 KVPGIGYKTREKLKALGLVNVRDLQLYPLSDLVKEFGEMNAKRVQNL--AC-GIDDSPVTPAGPP 304

  Fly   562 KTVSAEMNFGIRFTNSVE-----CEQFLCQLSEEV--------TKRLVEIR----------RKAR 603
            :::|.|.:|  :..:::|     .|:.|..|:|.:        |.||. ||          |::|
Zfish   305 QSLSDEDSF--KKMSTLEEVLKKIEELLINLTERMHKDGRQPHTLRLT-IRKYTVTNRWFNRESR 366

  Fly   604 S------INLKIMVRAAEAP---VETSKYMGHGVCD--------IIN------------KSSLIK 639
            .      ..|||...::||.   :..|..:.|.:.|        ::|            |||:..
Zfish   367 QCPIPNHTGLKITGGSSEAVPQLLSLSMKLFHKMVDPHQPFHLTLLNVCFSNLQAKSSSKSSIAS 431

  Fly   640 YATDDVNVITTVVLDLMKDADIPPDELRGLGIHLTRLEDANEVRKENNIKEMFGKMSEMRKDKPI 704
            :.|.. :..||.:.....|:|:.......   |.|:.    :|..:|:           :..||:
Zfish   432 FFTHK-SPSTTQIPSQQVDSDLCESVASS---HFTQA----DVLHKND-----------KAWKPV 477

  Fly   705 PQGAVGDKSIGDDKVNKPLVFENKPK----PREPRNVLSMLTAAAVSRKSVTEDRSQR----GTS 761
            ...::.........||        ||    ||:|           ||..|...:.:.|    .::
Zfish   478 NNTSISPTQTQSTSVN--------PKSSLSPRQP-----------VSEHSQHANINIRPPCLSSA 523

  Fly   762 KPITRPLSLVPKLDEDVLAQLPEDIRLEVIANREEHLCIAEYDGYRSP---------QYPTLRSP 817
            ...|....|.|.:|.||...|||.|::|::::      ..:.|.:..|         ..||..|.
Zfish   524 PKTTLHFKLPPNVDADVFKLLPEHIQMELMSS------FKKGDSFYRPADTEDVDPEHQPTFASR 582

  Fly   818 PLLNPYVTTNVSPLKATDLKPSTSRAAVARLQKRKERKEQEHY--------IRSDQIVADYIDDL 874
            ....|              ||..|...|.........:..:::        ..|:.::....||:
Zfish   583 QPKTP--------------KPCESAVNVCTNSASNPHELSQNFSSPQSIPEFSSELVMVTESDDI 633

  Fly   875 PDF-----------VNPHILKLISHPVEMPELLMGDNYKDLLNDWVSREEVPKPNDVDLILKQVS 928
            |..           |:|::..      ::|    .|..::||.:|..:..|.|...........|
Zfish   634 PHSTQAIQPEVPANVDPYVFS------QLP----ADVQRELLTEWRQQRPVLKIPSKHSHKSSNS 688

  Fly   929 RMIKNDQLDHVC-DVMKYW 946
            |..|.......| :::||:
Zfish   689 RDRKTSTKGSQCNNILKYF 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rev1	NP_612047.1	BRCT_Rev1	39..121	CDD:349351
		PolY_Rev1	218..676	CDD:176455	116/490 (24%)
		Rev1_C	890..985	CDD:213388	13/58 (22%)
poli	NP_001017834.1	PolY_Pol_iota	40..418	CDD:176457	105/436 (24%)
		Rev1_UBM2	<645..672	CDD:412037	7/36 (19%)