DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3402 and Sdcbp

DIOPT Version :9

Sequence 1:	NP_612045.1	Gene:	CG3402 / 38077	FlyBaseID:	FBgn0035148	Length:	123	Species:	Drosophila melanogaster
Sequence 2:	NP_114192.1	Gene:	Sdcbp / 83841	RGDID:	621497	Length:	300	Species:	Rattus norvegicus

Alignment Length:	149	Identity:	38/149 - (25%)
Similarity:	57/149 - (38%)	Gaps:	59/149 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PITLH----KEKDYDQEGREILKCGFKIGGGIDQDYK-----KSPQGYTDYGIYVTEVHEGSPAA 75
            |:|.:    :..:..|..||::.|.       |||.|     ||    .|.||:|..|...|||:
  Rat    97 PVTGNDAGIRRAEIKQGIREVILCK-------DQDGKIGLRLKS----VDNGIFVQLVQANSPAS 150

  Fly    76 RAGLRIHDKILQCNG-------------------------------YDFTMVTHKKA---VSYIR 106
            ..|||..|::||.||                               ::.|:..||.:   |.:|.
  Rat   151 LVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTVTMHKDSSGHVGFIF 215

  Fly   107 KNPILNMLV-----ARKGV 120
            |:..:..:|     ||.|:
  Rat   216 KSGKITSIVKDSSAARNGL 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3402	NP_612045.1	PDZ_signaling	21..116	CDD:238492	34/142 (24%)
Sdcbp	NP_114192.1	Interaction with PDCD6IP. /evidence=ECO:0000250\|UniProtKB:O08992	2..104		2/6 (33%)
		LYPX(n)L motif 1. /evidence=ECO:0000250\|UniProtKB:O08992	3..7
		LYPX(n)L motif 2. /evidence=ECO:0000250\|UniProtKB:O08992	47..51
		LYPX(n)L motif 3. /evidence=ECO:0000250\|UniProtKB:O08992	51..55
		PDZ_signaling	114..193	CDD:238492	25/89 (28%)
		PDZ_signaling	198..271	CDD:238492	10/37 (27%)
		phosphatidylinositol-4, 5-bisphosphate-binding. /evidence=ECO:0000250\|UniProtKB:O00560	252..253
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000