Protein Alignment Reg-2 and Hdhd3

DIOPT Version :9

• Sequence 1: NP_612043.1
• Gene: Reg-2 / 38075
• FlyBaseID: FBgn0016715
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_077219.1
• Gene: Hdhd3 / 72748
• MGIID: 1919998
• Length: 251
• Species: Mus musculus
• Alignment Length: 242
• Identity: 68/242 - (28%)
• Similarity: 125/242 - (51%)
• Gaps: 14/242 - (5%)

  Fly     6 RFRLITFDVTNTLLQFRTTPGKQYGEIGALFGARCDNNELAKNFKANWYKMNRDYPNFGRDTNPQ 70
            :.||:|:||.:||::.|...|::|.......|...::..:.:.|:..:...:.::||:|....
Mouse     6 QMRLLTWDVKDTLIKLRRPVGEEYASKARAHGVVVEDITVEQAFRQAYRAQSHNFPNYGLSRG-- 68

  Fly    71 MEWQQWWRKLIAGTFAESGAAIPD-EKLHNFSNHLIELYKTSICWQPCNGSVELLQQLRKELKPE 134
            :..:|||:.::..||..:|  :|| :.:...::.|.|.:.:...||...|:...|:..||    .
Mouse    69 LTSRQWWKDVVLHTFRLAG--VPDAQAMTPVADQLYEDFSSPFTWQVLEGAEMTLKGCRK----R 127

  Fly   135 KCKLGVIANFDPRLPTLLQNTKLDQYLDFAINSYEVQAEKPDPQIFQKAMEKSGLKNLKPEECLH 199
            ..||.|::|||.||..:|....|.::.||.:.|..|...||||:||::|::::   .::|....|
Mouse   128 GLKLAVVSNFDRRLEDILTGLGLREHFDFVLTSEAVGCPKPDPRIFREALQRA---CVEPAVAAH 189

  Fly   200 IGDGPTTDYLAAKELGWHSALVHEKSYAYLVKKYGEDIDRDHVFPSL 246
            :||....||..::.:|.||.||  .....|.....:.:.::|:.|||
Mouse   190 VGDSYLCDYQGSQAVGMHSFLV--AGSEPLDSAVRDSVPKEHILPSL 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reg-2	NP_612043.1	DREG-2	8..220	CDD:274056	61/212 (29%)
		HAD_like	76..215	CDD:304363	42/139 (30%)
Hdhd3	NP_077219.1	DREG-2	8..210	CDD:274056	61/212 (29%)
		HAD_like	102..211	CDD:119389	37/115 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833524
Domainoid	1	1.000	66	1.000	Domainoid score	I9969
eggNOG	1	0.900	-	-		E1_COG1011
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	124	1.000	Inparanoid score	I4690
Isobase	1	0.950	-	0	Normalized mean entropy	S2956
OMA	1	1.010	-	-		QHG55252
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002375
OrthoInspector	1	1.000	-	-		otm42958
orthoMCL	1	0.900	-	-		OOG6_102573
Panther	1	1.100	-	-	LDO	PTHR46191
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1833
SonicParanoid	1	1.000	-	-		X2471
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.740