Protein Alignment Reg-2 and Nanp

DIOPT Version :10

• Sequence 1: NP_612043.1
• Gene: Reg-2 / 38075
• FlyBaseID: FBgn0016715
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_080362.1
• Gene: Nanp / 67311
• MGIID: 1914561
• Length: 248
• Species: Mus musculus
• Alignment Length: 589
• Identity: 106/589 - (17%)
• Similarity: 199/589 - (33%)
• Gaps: 154/589 - (26%)

  Fly    67 FLST-LW------ISHVDGDKGRSLVDS----VEKGEPDDER-ADETAESVDATSLESTSVHSNP 119
            |||: :|      |:.:.|.|.:....|    |:.|...... .|..|.......|::..|||..
Mouse    14 FLSSFVWNGRQFDINSLKGKKRKRWFKSRSFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQR 78

  Fly   120 GLS------SDVDIAAAGESKGSETILKQLEVDNTIV-----IVGNVTESKDN----VPMKQSEI 169
            ..|      ||.|::....|:.| :|...:..|:.||     ::.::...::|    ..::|...
Mouse    79 RESFLYRSDSDYDLSPKSMSRNS-SIASDIHGDDMIVTPFAQVLASLRTVRNNFAALTNVQQERS 142

  Fly   170 NN------NTVPGNDTETTGSKLDQLSRAVPLGLD-------------EFKSRASNSRDKSLSGQ 215
            ||      |..|...|..|.....:|:......||             .....|||...:.|:.:
Mouse   143 NNKRSPMCNPPPITKTSYTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRE 207

  Fly   216 VTGVIHRMEPGGKEYNYAAASKGAKVLSSNKEAKGASSIICRDKDKYLRNPCSTEG--------- 271
            :|.:......|.:...|.:::    .|....|.:..|....:||:|..|......|
Mouse   208 LTHLSEMSRSGNQVSEYISST----FLDKQNEVEMPSPQSQKDKEKKKRPMSQISGVKKLTHSSS 268

  Fly   272 -------KFVVIELSEETL-----------VNTIKIANFEHYSSN----------LKDFEILGTL 308
                   :|.|...:|:.|           :|..|::.|   |.|          .::.::|.|.
Mouse   269 LTNSNIPRFGVKTETEDELAKELEDVNKWGLNVFKVSEF---SGNRPLTVMMYTIFQERDLLKTF 330

  Fly   309 VYPTDTWV----HLGNFTALNMKHEQNFTFADPKWVRYLKLNLLSHYGSE-FYCTLSLLEVYGVD 368
            ..|.||::    .|.:....::.:..|...||.....::   |||....| .:..|.:|......
Mouse   331 KIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHV---LLSTPALEAVFTDLEILAAIFAS 392

  Fly   369 AVERM----LEDLISIQDKNILKLQEGDTEQKEK-------KTMQAKESFESDEDKSKQKEKEQE 422
            |:..:    :.:...|...:.|.|...|:...|.       |.:| :|:.:..::.:|::.:...
Mouse   393 AIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ-EENCDIFQNLTKKQRQSLR 456

  Fly   423 ASPENAVVKDEVSLEKRKLPDPVEEIKHQPGSRMPGDTVLKILMQKIRSLDVSLSVLESYLEERS 487
            ....:.|:..::|.....|.|                  ||.:::..:.....:.:|::|.:...
Mouse   457 KMVIDIVLATDMSKHMNLLAD------------------LKTMVETKKVTSSGVLLLDNYSDRIQ 503

  Fly   488 LKYGMIFKEMDLEASKREKEVETMRLEVEGMKEREENTKKEAMEMRKWRMRVETE-LEKAENEKE 551
            :...|:.. .||                       .|..|.....|:|..|:..| ..:.:.|:|
Mouse   504 VLQNMVHC-ADL-----------------------SNPTKPLQLYRQWTDRIMEEFFSQGDRERE 544

  Fly   552 KVKE 555
            :..|
Mouse   545 RGME 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reg-2	NP_612043.1	DREG-2	8..220	CDD:274056	42/198 (21%)
Nanp	NP_080362.1	CTE7	6..234	CDD:274057	45/224 (20%)