Protein Alignment Reg-2 and bigr-1

DIOPT Version :10

• Sequence 1: NP_612043.1
• Gene: Reg-2 / 38075
• FlyBaseID: FBgn0016715
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001254294.1
• Gene: bigr-1 / 174706
• WormBaseID: WBGene00009512
• Length: 226
• Species: Caenorhabditis elegans
• Alignment Length: 261
• Identity: 54/261 - (20%)
• Similarity: 94/261 - (36%)
• Gaps: 71/261 - (27%)

  Fly     1 MRSLSRFRLITFDVTNTLLQFRTTPGKQYGEIGALFGARCDNNELAKNFKANWYKMNRD--YPNF 63
            |....:.:.:.:|....||.:.....|                         |..|:|.  .|:.
 Worm     1 MTMTQQIKAVVYDFGGVLLSYEGVMEK-------------------------WVAMSRSLGLPDD 40

  Fly    64 G-RDTNPQMEWQQWW---RKLIAGTFA----ESGAAIPDEKLHNFSNHL---IELYKTSICWQPC 117
            . ...:..:|:.||.   |.|..||..    |.|..:...| |.:.|.|   :.:...:.|.:..
 Worm    41 AVHSESVGIEFSQWLGPDRSLFLGTLTVDDLEGGLFLQYLK-HKYGNKLTDNVVIKPFTECLRGE 104

  Fly   118 NGSVELLQQLRKELKPEK-CKLGVIAN--------FDPRLPTLLQNTKLDQYLDFAINSYEVQAE 173
            |..:....|...|:..:| .|..::.|        .:.|||..|  |..|:.::..:.    ...
 Worm   105 NVKIHKNMQKTVEILHKKGFKTAMLTNNMFLDKEHKETRLPCDL--THFDEVVESCLE----HLM 163

  Fly   174 KPDPQIFQKAMEKSGLKNLKPEECLHIGDGPTTDYLAAKELGWHSALVHEKSYAYLVKKYGEDID 238
            |||.:.:....::.|   :||||.:.: |....:..||::|||::.||             |||:
 Worm   164 KPDARFYHLVEKRLG---VKPEEIVFL-DDLHENIEAAEKLGWNTILV-------------EDIE 211

  Fly   239 R 239
            :
 Worm   212 K 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reg-2	NP_612043.1	DREG-2	8..220	CDD:274056	48/233 (21%)
bigr-1	NP_001254294.1	HAD-1A3-hyp	6..223	CDD:274054	53/256 (21%)