back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Reg-2 and NANP

DIOPT Version :9

Sequence 1:	NP_612043.1	Gene:	Reg-2 / 38075	FlyBaseID:	FBgn0016715	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_689880.1	Gene:	NANP / 140838	HGNCID:	16140	Length:	248	Species:	Homo sapiens

Alignment Length:	227	Identity:	54/227 - (23%)
Similarity:	88/227 - (38%)	Gaps:	58/227 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LSRFRLITFDVTNTLLQFRTTPGKQYGEIGALFGAR----------CDNNELAKNFKANWYKMNR 58
            |||.|.:.||:.|||:.......:...|:..|..::          ||..:: |..|..::..|.
Human     3 LSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQV-KLSKECFHPYNT 66

  Fly    59 DYPNFGRDTNPQMEWQQWWRKLIAGTFAESGAAIPDEKLHNFSNHLIELYKTSICWQP------- 116
            ...:. |.::        |.:.|..|  :.|||  :.||..      |.|   ..|:.
Human    67 CITDL-RTSH--------WEEAIQET--KGGAA--NRKLAE------ECY---FLWKSTRLQHMT 109

  Fly   117 -CNGSVELLQQLRKELKPEKCKLGVIANFDPRLPTLLQNTKLD-----QYLDFAINSYEVQAEKP 175
             ......:|.:||||:     :|.::.|.|.:    .|..|::     .|.|..:...|.:.|||
Human   110 LAEDVKAMLTELRKEV-----RLLLLTNGDRQ----TQREKIEACACQSYFDAVVVGGEQREEKP 165

  Fly   176 DPQIFQKAMEKSGLKNLKPEECLHIGDGPTTD 207
            .|.||...   ..|..::|.:|:.:||...||
Human   166 APSIFYYC---CNLLGVQPGDCVMVGDTLETD 194

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.