DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13893 and sec14l5

DIOPT Version :9

Sequence 1:	NP_612042.3	Gene:	CG13893 / 38074	FlyBaseID:	FBgn0035146	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_031749906.1	Gene:	sec14l5 / 493292	XenbaseID:	XB-GENE-953433	Length:	793	Species:	Xenopus tropicalis

Alignment Length:	335	Identity:	84/335 - (25%)
Similarity:	162/335 - (48%)	Gaps:	32/335 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LPEISEEQRAILEKFRKQMDDALVGTH-----DDYFLVRWLRARKWNLEAAEKMLRASLKTRAMW 64
            |.:::..|.:.|.:.|:.:.:    ||     .|..::|:||||.:|::.|.::|..||..|...
Frog   248 LGDLTPLQESCLIRLRQWLQE----THKGKIPKDEHILRFLRARDFNIDKAREILCQSLTWRKQH 308

  Fly    65 NVDN-IEKWDPPKALQEYLPYGLMGYDNEGSPVLVCPFANFDMWGMMHCVTRFEFQKYLVLLLER 128
            :||. :..||||:.|.:|...|...:|.:|.|:.|......|..|::..:......::::.:.|.
Frog   309 HVDYLLSTWDPPQVLHDYYAGGWHHHDRDGRPLYVLRLGQMDTKGLVRALGEESLLRHVLSINEE 373

  Fly   129 FMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAWRPAAECVISTVKQYEANFPELLKMCYIINA 193
            .::...:.:...|..........|::.:|:: :.|||..:.::..::..|||:||.|....|:.|
Frog   374 GLRRCEENTNIFGRPISSWTCLVDLEGLNMR-HLWRPGVKALLRIIEVVEANYPETLGRLLILRA 437

  Fly   194 PKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVNRKAFPKAWGGEMVDRNGDPQCKA 258
            |::|.|.:.:|..|:||||..|.:||.....:....|..:::::..|...|||         |..
Frog   438 PRVFPVLWTLVSPFIDENTRKKFLIYAGNDYQGPGGLIDYIDKEVIPDFLGGE---------CMC 493

  Fly   259 LMVWGGKLPEELYIDQSSQQSDRD---------FVEAQVPKGDKLKLHFKVNVEEQKILSWEFRT 314
            .:..||.:|:.||  ::.::.:.|         :..|.|.||...::..:: |:...:::|:|..
Frog   494 EVSEGGMVPKALY--RTPEELENDDIRLWTETIYQSASVFKGSPHEILIQI-VDASSVITWDFDV 555

  Fly   315 FDYDIKFGIY 324
            ...||.|.||
Frog   556 CKGDIVFNIY 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	13/45 (29%)
		SEC14	75..246	CDD:238099	40/170 (24%)
		GOLD_2	303..381	CDD:290608	7/22 (32%)
sec14l5	XP_031749906.1	PRELI	17..173	CDD:398400
		CRAL_TRIO_N	256..301	CDD:215024	13/48 (27%)
		CRAL_TRIO	326..490	CDD:395525	38/164 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	1	1.000	-	-		FOG0000197
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920