DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13893 and sec14l1

DIOPT Version :9

Sequence 1:	NP_612042.3	Gene:	CG13893 / 38074	FlyBaseID:	FBgn0035146	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_957392.1	Gene:	sec14l1 / 394073	ZFINID:	ZDB-GENE-040426-801	Length:	697	Species:	Danio rerio

Alignment Length:	328	Identity:	78/328 - (23%)
Similarity:	157/328 - (47%)	Gaps:	32/328 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 QRAILEKFRKQMDDALVGTH-----DDYFLVRWLRARKWNLEAAEKMLRASLKTRAMWNVD-NIE 70
            |.:.|.:.|:.:.:    ||     .|..::|:||:|.:|||.|::.|..:|..|....:| .::
Zfish   237 QESCLIRLRQWLQE----THKGKIPKDQHVLRFLRSRDFNLEKAKEALCQTLTWRKQHQIDFLLD 297

  Fly    71 KWDPPKALQEYLPYGLMGYDNEGSPVLVCPFANFDMWGMMHCVTRFEFQKYLVLLLERFMKIAYD 135
            .|..|:.||:|...|...:|.:|.|:.:......|..|::..:......::::.:.|..::...:
Zfish   298 TWQSPQPLQDYYTGGWHHHDKDGRPLYILRLGQMDTKGLVRALGEETLLRHVLSINEEGLRRCEE 362

  Fly   136 QSQKHGWRARQLVVFFDMQDVNLKQYAWRPAAECVISTVKQYEANFPELLKMCYIINAPKLFSVA 200
            .::..|..........|::.:|:: :.|||..:.::..::...||:||.|....|:.||::|.|.
Zfish   363 NTKIFGKPISCWTCLVDLEGLNMR-HLWRPGIKALLRMIEVVGANYPETLGRLLILRAPRVFPVL 426

  Fly   201 FNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVNRKAFPKAWGGEMVDRNGDPQCKALMVWGGK 265
            :.:|..|:||||..|.:||.....:....|..::|:...|...|       ||..|.  :..||.
Zfish   427 WTLVSPFIDENTRKKFLIYAGNDYQGPGGLVDYINKDCIPDFLG-------GDSMCD--IPEGGL 482

  Fly   266 LPEELYIDQSSQQSDRDFVE---------AQVPKGDKLKLHFKVNVEEQKILSWEFRTFDYDIKF 321
            :|:.||  :::::.:.:.|:         |.|.||...::..:: .:...:::|:|.....|:.|
Zfish   483 VPKSLY--RTAEELENEEVKLWNETIYKSASVLKGAPHEVLIEI-TDVSSVITWDFDVCKGDMIF 544

  Fly   322 GIY 324
            .||
Zfish   545 NIY 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	14/45 (31%)
		SEC14	75..246	CDD:238099	40/170 (24%)
		GOLD_2	303..381	CDD:290608	6/22 (27%)
sec14l1	NP_957392.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	238..283	CDD:215024	14/48 (29%)
		CRAL_TRIO	308..472	CDD:279044	37/171 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586530
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	1	1.000	-	-		FOG0000197
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850