DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13893 and Clvs1

DIOPT Version :9

Sequence 1:	NP_612042.3	Gene:	CG13893 / 38074	FlyBaseID:	FBgn0035146	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001102439.1	Gene:	Clvs1 / 366311	RGDID:	1564200	Length:	354	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	59/266 - (22%)
Similarity:	118/266 - (44%)	Gaps:	38/266 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SGPLPEISEEQRA-------ILEKFRKQMDDALVG-------THDDYFLVRWLRARKWNLEAAEK 52
            :|..|:..|:.|.       :|.:..:|:.|.::.       ..||.|::|:|||||::...|.:
  Rat    28 AGLSPDTIEKARLELNENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFR 92

  Fly    53 MLRASLKTRAMWNVD---NIEKWDP--PKALQEYLPYGLMGYDNEGSPVLVCPFANFDMWGMMHC 112
            :|....:.|.: |:|   |.:..||  .:||.:..|..|...|:.|..:|:...||:|.
  Rat    93 LLAQYFQYRQL-NLDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAANWDQ------ 150

  Fly   113 VTRFEFQKYL-VLLLERFMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAWRPAAECVISTVKQ 176
             :|..|...| .:||...:.|...:.|.:|:     ::..|..:.:.|| |.:.....:...::.
  Rat   151 -SRNSFTDILRAILLSLEVLIEDPELQINGF-----ILIIDWSNFSFKQ-ASKLTPSILKLAIEG 208

  Fly   177 YEANFPELLKMCYIINAPKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVNRKAFPK 241
            .:.:||......:.:|.|......:.::|.||.:.|..:|.::.:.::    .|...::.:..|.
  Rat   209 LQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLN----SLHQLIHPEFLPS 269

  Fly   242 AWGGEM 247
            .:||.:
  Rat   270 EFGGTL 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	14/47 (30%)
		SEC14	75..246	CDD:238099	34/171 (20%)
		GOLD_2	303..381	CDD:290608
Clvs1	NP_001102439.1	CRAL_TRIO_N	51..97	CDD:215024	13/45 (29%)
		CRAL_TRIO	125..274	CDD:395525	32/165 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	317..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910