DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13893 and Sec14l1

DIOPT Version :9

Sequence 1:	NP_612042.3	Gene:	CG13893 / 38074	FlyBaseID:	FBgn0035146	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001101779.1	Gene:	Sec14l1 / 360668	RGDID:	1563123	Length:	720	Species:	Rattus norvegicus

Alignment Length:	378	Identity:	92/378 - (24%)
Similarity:	175/378 - (46%)	Gaps:	45/378 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LPEISEEQRAILEKFRKQMDDALVGTH-----DDYFLVRWLRARKWNLEAAEKMLRASLKTRAMW 64
            |.:::..|.:.|.:.|:.:.:    ||     .|..::|:||||.:|::.|.:::..||..|...
  Rat   249 LGDLTPLQESCLIRLRQWLQE----THKGKIPKDEHILRFLRARDFNIDKAREIMCQSLTWRKQH 309

  Fly    65 NVDNI-EKWDPPKALQEYLPYGLMGYDNEGSPVLVCPFANFDMWGMMHCVTRFEFQKYLVLLLER 128
            .||.| :.|.||:.||:|...|...:|.:|.|:.|......|..|::..:......:|::.:.|.
  Rat   310 QVDYILDTWTPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEE 374

  Fly   129 FMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAWRPAAECVISTVKQYEANFPELLKMCYIINA 193
            .::...:.::..|..........|::.:|:: :.|||..:.::..::..|||:||.|....|:.|
  Rat   375 GLRRCEENTKVFGRPISSWTCLVDLEGLNMR-HLWRPGVKALLRIIEVVEANYPETLGRLLILRA 438

  Fly   194 PKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVNRKAFPKAWGGEMVDRNGDPQCKA 258
            |::|.|.:.:|..|:|:||..|.:||.....:....|..:::::..|....||         |..
  Rat   439 PRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGE---------CMC 494

  Fly   259 LMVWGGKLPEELYIDQSSQQSDRD---------FVEAQVPKGDKLKLHFKVNVEEQKILSWEFRT 314
            .:..||.:|:.||  ::.::.:.:         :..|.|.||...::..:: |:...:::|:|..
  Rat   495 DVPEGGLVPKSLY--RTPEELENEDLKLWTETIYQSASVFKGAPHEILIQI-VDAASVITWDFDV 556

  Fly   315 FDYDIKFGIYSVDDKTGEKRSEVPLGTVYSNEMDEIGYIS-TRPNTTYTVVFD 366
            ...||.|.||.      .|||..|      .:.|.:|..| |.|......:.|
  Rat   557 CKGDIVFNIYH------SKRSPQP------PKKDSLGAHSITSPGGNNVQLID 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	12/45 (27%)
		SEC14	75..246	CDD:238099	40/170 (24%)
		GOLD_2	303..381	CDD:290608	17/65 (26%)
Sec14l1	NP_001101779.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	257..302	CDD:215024	12/48 (25%)
		CRAL_TRIO	327..491	CDD:279044	37/164 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	1	1.000	-	-		FOG0000197
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750