DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13893 and ttpal

DIOPT Version :9

Sequence 1:	NP_612042.3	Gene:	CG13893 / 38074	FlyBaseID:	FBgn0035146	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_021325407.1	Gene:	ttpal / 321577	ZFINID:	ZDB-GENE-030131-296	Length:	360	Species:	Danio rerio

Alignment Length:	277	Identity:	65/277 - (23%)
Similarity:	111/277 - (40%)	Gaps:	74/277 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PEISEEQRAILE-----KFR--KQMDDALVGTH-------DDYFLVRWLRARKWNLEAAEKMLRA 56
            ||:..:.|..|:     :.|  :.:.|.::..|       ||.||:|:|||||::.:.|.::|..
Zfish    55 PELVAKAREELQEKPEWRLRDVQALRDMILKDHPNLRTRLDDAFLLRFLRARKFDYDRALQLLLN 119

  Fly    57 SLKTRAMWNVDNIEKWDPPKALQEYLPYGL-----MGY-------DNEGSPVLVC---------- 99
            ...:|..|          |:..|:..|..:     :|:       |.:|..:| |
Zfish   120 YHASRRAW----------PEVFQDLKPSTVKHVLDLGFLTVLPRPDPQGRYIL-CLRPGKWKPND 173

  Fly   100 -PFANFDMWGMMHCVTRFEFQKYLVLLLERFMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAW 163
             ||.              :..:.:.|.||:.  |..:::|.:|     :|:..|...|.|.| |.
Zfish   174 YPFV--------------DNIRAIYLTLEKL--IQPEETQVNG-----VVILVDYAGVGLSQ-AS 216

  Fly   164 RPAAECVISTVKQYEANFPELLKMCYIINAPKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQE 228
            .|........|...:..||..:|...|||.|::|...|.|:|.||.|....:.|::.|.:    .
Zfish   217 NPGPLLAKKVVGILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKMAERYVLHGSDL----A 277

  Fly   229 QLFSHVNRKAFPKAWGG 245
            .|...:.:...|:.:||
Zfish   278 SLHRVIPQSVLPQEYGG 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	16/54 (30%)
		SEC14	75..246	CDD:238099	44/194 (23%)
		GOLD_2	303..381	CDD:290608
ttpal	XP_021325407.1	CRAL_TRIO_N	74..120	CDD:215024	15/45 (33%)
ttpal	XP_021325407.1	SEC14	142..294	CDD:238099	39/178 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810