DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13893 and Ttpal

DIOPT Version :9

Sequence 1:	NP_612042.3	Gene:	CG13893 / 38074	FlyBaseID:	FBgn0035146	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001100007.1	Gene:	Ttpal / 296349	RGDID:	1305754	Length:	343	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	80/302 - (26%)
Similarity:	131/302 - (43%)	Gaps:	61/302 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RAILEKFRKQMDDALVGTHDDYFLVRWLRARKWNLEAAEKMLRASLKTRAMWN--VDNIEKWDPP 75
            :|:.:..||:. ..|..:.||.||:|:|||||::.:.|.::|......|..|.  ..|:.    |
  Rat    60 QALRDMVRKEY-PYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCRRSWPEVFSNLR----P 119

  Fly    76 KALQEYLPYGLMGY----DNEGSPVL-VCPFANFDMW-GMMHCVTRFEFQKYLVLLLERFMKIAY 134
            .||::.|..|.:..    |..|..|| :.|    |.| ...:.:|  |..:.:.|.||:.  |..
  Rat   120 SALKDVLNSGFLTVLPHTDPRGCHVLCIRP----DRWIPSNYPIT--ENIRAIYLTLEKL--IQS 176

  Fly   135 DQSQKHGWRARQLVVFFDMQDVNL-KQYAWRP-AAECVISTVKQYEANFPELLKMCYIINAPKLF 197
            :::|.:|     :|:..|.:.|:| |...:.| .|..||..::.   .||..:|..:|:|.|::|
  Rat   177 EETQVNG-----VVILADYKGVSLSKASHFGPFIARKVIGILQD---GFPIRIKAVHIVNEPRIF 233

  Fly   198 SVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVNRKAFPKAWGG----------------- 245
            ...|.|:|.||.|...::..::.|.:    ..|.:.:.|...||.:||
  Rat   234 KGIFAIIKPFLKEKIANRFFLHGSDL----SSLHTSLPRNILPKEYGGTAGELDTASWNAVLLAS 294

  Fly   246 --EMVDRNGDPQ--CKALMVWGGK--LPEELYIDQSSQQSDR 281
              :.|.....|:  |..|:   |:  |||.|..|.....|.|
  Rat   295 EDDFVKEFCQPESGCDGLL---GQPLLPEGLISDAQCDDSMR 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	15/40 (38%)
		SEC14	75..246	CDD:238099	49/197 (25%)
		GOLD_2	303..381	CDD:290608
Ttpal	NP_001100007.1	CRAL_TRIO_N	57..103	CDD:215024	16/43 (37%)
Ttpal	NP_001100007.1	SEC14	122..278	CDD:238099	46/175 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810