DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13893 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_612042.3	Gene:	CG13893 / 38074	FlyBaseID:	FBgn0035146	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001129182.2	Gene:	Sec14l5 / 287060	RGDID:	1564638	Length:	696	Species:	Rattus norvegicus

Alignment Length:	362	Identity:	91/362 - (25%)
Similarity:	169/362 - (46%)	Gaps:	30/362 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LPEISEEQRAILEKFRKQMDDALVGTH-----DDYFLVRWLRARKWNLEAAEKMLRASLKTRAMW 64
            |..:|..|.:.|.:.|:.:.:    ||     .|..::|:||||.::|:.|..||..||..|...
  Rat   235 LGHLSPMQESCLVQLRRWLQE----THKGKIPKDEHILRFLRARDFHLDKARDMLCQSLSWRKQH 295

  Fly    65 NVD-NIEKWDPPKALQEYLPYGLMGYDNEGSPVLVCPFANFDMWGMMHCVTRFEFQKYLVLLLER 128
            .|| .::.|.||..|||:...|....|.:|.|:.:......|..|:|..|......::::.:.|.
  Rat   296 QVDLLLQTWRPPAPLQEFYAGGWHYQDIDGRPLYILRLGQMDTKGLMKAVGEEALLQHVLSVNEE 360

  Fly   129 FMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAWRPAAECVISTVKQYEANFPELLKMCYIINA 193
            ..|.....:::.|..........|::.:|:: :.|||..:.::..::..|.|:||.|....|:.|
  Rat   361 GQKRCEGNTRQFGRPISSWTCLLDLEGLNMR-HLWRPGVKALLRMIEVVEDNYPETLGRLLIVRA 424

  Fly   194 PKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVNRKAFPKAWGGEMVDRNGDPQCKA 258
            |::|.|.:.:|..|::|||..|.:||.....:....|..::::...|...|||.|       |.
  Rat   425 PRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLVDYLDKDVIPDFLGGESV-------CN- 481

  Fly   259 LMVWGGKLPEELYI-DQSSQQSDR------DFVEAQVPKGDKLKLHFKVNVEEQKILSWEFRTFD 316
             :..||.:|:.||: ::..:|:|:      .:..|.|.:|...::..:: .|.:.:::|:|....
  Rat   482 -VPEGGMVPKSLYLTEEEQEQADQLRQWSETYHSASVLRGSPHEVAMEI-PEGESVITWDFDILR 544

  Fly   317 YDIKFGIYSVDDKTGEKRSEVPLGTVYSNEMDEIGYI 353
            .|:.|.:|..  |...|.|....|...|.::.:..:|
  Rat   545 GDVVFSLYHA--KQAPKLSPQEPGVRASGQLIDKNWI 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	14/45 (31%)
		SEC14	75..246	CDD:238099	41/170 (24%)
		GOLD_2	303..381	CDD:290608	12/51 (24%)
Sec14l5	NP_001129182.2	PRELI	17..173	CDD:309720
		Amidase	<179..309	CDD:327489	25/77 (32%)
		CRAL_TRIO_N	243..288	CDD:215024	14/48 (29%)
		CRAL_TRIO	314..477	CDD:306996	37/163 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345465
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	1	1.000	-	-		FOG0000197
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750