Protein Alignment CG13893 and SEC14L4

DIOPT Version :10

• Sequence 1: NP_612042.3
• Gene: CG13893 / 38074
• FlyBaseID: FBgn0035146
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_777637.1
• Gene: SEC14L4 / 284904
• HGNCID: 20627
• Length: 406
• Species: Homo sapiens
• Alignment Length: 406
• Identity: 136/406 - (33%)
• Similarity: 222/406 - (54%)
• Gaps: 20/406 - (4%)

  Fly     1 MSGPLPEISEEQRAILEKFRKQMDDAL--VGTHDDYFLVRWLRARKWNLEAAEKMLRASLKTRAM 63
            ||..:.::|.:|:..|.:||:.:.|.|  :...|||||:||||||.::|:.:|.|||..::.|..
Human     1 MSSRVGDLSPQQQEALARFRENLQDLLPILPNADDYFLLRWLRARNFDLQKSEDMLRRHMEFRKQ 65

  Fly    64 WNVDNIEKWDPPKALQEYLPYGLMGYDNEGSPVLVCPFANFDMWGMMHCVTRFEFQKYLVLLLER 128
            .::|||..|.||:.:|.|...||.|||.||.||......:.|..|::...::.:..:..:.:.|.
Human    66 QDLDNIVTWQPPEVIQLYDSGGLCGYDYEGCPVYFNIIGSLDPKGLLLSASKQDMIRKRIKVCEL 130

  Fly   129 FMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAWRPAAECVISTVKQYEANFPELLKMCYIINA 193
            .:.....|:||.|.:....::.|||:.::|| :.|:||.|.........|||:||.||...:|.|
Human   131 LLHECELQTQKLGRKIEMALMVFDMEGLSLK-HLWKPAVEVYQQFFSILEANYPETLKNLIVIRA 194

  Fly   194 PKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVNRKAFPKAWGGEMVDRNGDPQCKA 258
            ||||.||||:||.|:.|.|..||||..   |.|:::|...::....|..:||.|.|.:|:|:|..
Human   195 PKLFPVAFNLVKSFMSEETRRKIVILG---DNWKQELTKFISPDQLPVEFGGTMTDPDGNPKCLT 256

  Fly   259 LMVWGGKLPEELYI-DQSSQQSDRDFVEAQVPKGDKLKLHFKVNVEEQKILSWEFRTFDYDIKFG 322
            .:.:||::|:..|: :|...|.:.   ...|.:|..|::..:: :....:|.|:|.:...||.||
Human   257 KINYGGEVPKSYYLCEQVRLQYEH---TRSVGRGSSLQVENEI-LFPGCVLRWQFASDGGDIGFG 317

  Fly   323 IYSVDDKTGEKRS-----EVPLGTVYSNEM-DEIGYISTRPNTTYTVVFDNSASYLRSKKLRYWV 381
            :: :..|.||::|     ||.....|:..| .|.|.::......|.:.|||:.|.:.:|||.|.|
Human   318 VF-LKTKMGEQQSAREMTEVLPSQRYNAHMVPEDGSLTCLQAGVYVLRFDNTYSRMHAKKLSYTV 381

  Fly   382 DLISEEEEGISELTTQ 397
            :::..::  .||.|.|
Human   382 EVLLPDK--ASEETLQ 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	21/42 (50%)
		CRAL_TRIO	81..245	CDD:459890	56/163 (34%)
		GPCR_chapero_1	303..381	CDD:480652	26/83 (31%)
SEC14L4	NP_777637.1	CRAL_TRIO_N	13..59	CDD:215024	21/45 (47%)
		SEC14	76..244	CDD:214706	60/171 (35%)
		GPCR_chapero_1	284..381	CDD:480652	29/98 (30%)