Protein Alignment CG13893 and SEC14L3

DIOPT Version :9

• Sequence 1: NP_612042.3
• Gene: CG13893 / 38074
• FlyBaseID: FBgn0035146
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: XP_011528430.1
• Gene: SEC14L3 / 266629
• HGNCID: 18655
• Length: 412
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 124/421 - (29%)
• Similarity: 213/421 - (50%)
• Gaps: 40/421 - (9%)

  Fly     1 MSGPLPEISEEQRAILEKFRKQMDDAL--VGTHDDYFLVRWLRARKWNLEAAEKMLRASLKTRAM 63
            |||.:.::|.:|...|.|||:.:.|.|  :...|||||:||||||.::|:.:|.:||..::.|..
Human     1 MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKYMEFRKT 65

  Fly    64 WNVDNIEKWDPPKALQEYLPYGLMGYDNEGSPVLVCPFANFDMWGMMHCVTRFEFQKYLVLLLER 128
            .::|:|..|.||:.:|:|:|.||.|||.:|.||........|..|::..||:.:..|..:...||
Human    66 MDIDHILDWQPPEVIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCER 130

  Fly   129 FMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAWRPAAECVISTVKQYEANFPELLKMCYIINA 193
            .:.....|:::.|.:...:|:.||.:.:.||.: |:|..|.........|.|:||.||...|:.|
Human   131 ILHECDLQTERLGKKIETIVMIFDCEGLGLKHF-WKPLVEVYQEFFGLLEENYPETLKFMLIVKA 194

  Fly   194 PKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVNRKAFPKAWGGEMVDRNGDPQCKA 258
            .|||.|.:|::|.||.|:|..||::..   :.|:|.|...::.:..|..:||.:.|.:|:|:|..
Human   195 TKLFPVGYNLMKPFLSEDTRRKIIVLG---NNWKEGLLKLISPEELPAQFGGTLTDPDGNPKCLT 256

  Fly   259 LMVWGGKLPEELYI-DQSSQQSDRDFVEAQVPKGDKLKLHFKVNVEEQKILSWEFRTFDYDIKFG 322
            .:.:||::|:.:|: ||...|.:.   ..|:.:|...::.::: :....:|.|:|.:...||.||
Human   257 KINYGGEIPKSMYVRDQVKTQYEH---SVQINRGSSHQVEYEI-LFPGCVLRWQFSSDGADIGFG 317

  Fly   323 IYSVDDKTGEKRSEVPLGTVYSNEMDEIGYISTRPNTTYTVVFDNSASYLRSKKLRYWVDLISEE 387
            :: :..|.||::.        :.||.::     .|:..|..........|...:...:|    |.
Human   318 VF-LKTKMGERQR--------AGEMTDV-----LPSQRYNAHMVPEDGNLTCSEAGVYV----ES 364

  Fly   388 EEGIS-----------ELTTQMDNTQIANQQ 407
            |.|.|           ||.....|:|:...|
Human   365 ESGKSCCHLPVIICSHELQNSHSNSQVMAYQ 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	21/42 (50%)
		SEC14	75..246	CDD:238099	54/170 (32%)
		GOLD_2	303..381	CDD:290608	15/77 (19%)
SEC14L3	XP_011528430.1	CRAL_TRIO_N	13..59	CDD:215024	21/45 (47%)
		SEC14	76..245	CDD:214706	56/172 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151946
Domainoid	1	1.000	63	0.304	Domainoid score	I10238
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	224	1.000	Inparanoid score	I3520
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52454
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	1	1.000	-	-		FOG0000197
OrthoInspector	1	1.000	-	-		otm41197
orthoMCL	1	0.900	-	-		OOG6_102488
Panther	1	1.100	-	-	LDO	PTHR23324
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1304
SonicParanoid	1	1.000	-	-		X1090
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800