Protein Alignment CG13893 and SEC14L3

DIOPT Version :10

• Sequence 1: NP_612042.3
• Gene: CG13893 / 38074
• FlyBaseID: FBgn0035146
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: XP_011528430.1
• Gene: SEC14L3 / 266629
• HGNCID: 18655
• Length: 412
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 124/421 - (29%)
• Similarity: 213/421 - (50%)
• Gaps: 40/421 - (9%)

  Fly     1 MSGPLPEISEEQRAILEKFRKQMDDAL--VGTHDDYFLVRWLRARKWNLEAAEKMLRASLKTRAM 63
            |||.:.::|.:|...|.|||:.:.|.|  :...|||||:||||||.::|:.:|.:||..::.|..
Human     1 MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKYMEFRKT 65

  Fly    64 WNVDNIEKWDPPKALQEYLPYGLMGYDNEGSPVLVCPFANFDMWGMMHCVTRFEFQKYLVLLLER 128
            .::|:|..|.||:.:|:|:|.||.|||.:|.||........|..|::..||:.:..|..:...||
Human    66 MDIDHILDWQPPEVIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCER 130

  Fly   129 FMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAWRPAAECVISTVKQYEANFPELLKMCYIINA 193
            .:.....|:::.|.:...:|:.||.:.:.||.: |:|..|.........|.|:||.||...|:.|
Human   131 ILHECDLQTERLGKKIETIVMIFDCEGLGLKHF-WKPLVEVYQEFFGLLEENYPETLKFMLIVKA 194

  Fly   194 PKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVNRKAFPKAWGGEMVDRNGDPQCKA 258
            .|||.|.:|::|.||.|:|..||::..   :.|:|.|...::.:..|..:||.:.|.:|:|:|..
Human   195 TKLFPVGYNLMKPFLSEDTRRKIIVLG---NNWKEGLLKLISPEELPAQFGGTLTDPDGNPKCLT 256

  Fly   259 LMVWGGKLPEELYI-DQSSQQSDRDFVEAQVPKGDKLKLHFKVNVEEQKILSWEFRTFDYDIKFG 322
            .:.:||::|:.:|: ||...|.:.   ..|:.:|...::.::: :....:|.|:|.:...||.||
Human   257 KINYGGEIPKSMYVRDQVKTQYEH---SVQINRGSSHQVEYEI-LFPGCVLRWQFSSDGADIGFG 317

  Fly   323 IYSVDDKTGEKRSEVPLGTVYSNEMDEIGYISTRPNTTYTVVFDNSASYLRSKKLRYWVDLISEE 387
            :: :..|.||::.        :.||.::     .|:..|..........|...:...:|    |.
Human   318 VF-LKTKMGERQR--------AGEMTDV-----LPSQRYNAHMVPEDGNLTCSEAGVYV----ES 364

  Fly   388 EEGIS-----------ELTTQMDNTQIANQQ 407
            |.|.|           ||.....|:|:...|
Human   365 ESGKSCCHLPVIICSHELQNSHSNSQVMAYQ 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	21/42 (50%)
		CRAL_TRIO	81..245	CDD:459890	51/163 (31%)
		GPCR_chapero_1	303..381	CDD:480652	15/77 (19%)
SEC14L3	XP_011528430.1	CRAL_TRIO_N	13..59	CDD:215024	21/45 (47%)
		SEC14	76..245	CDD:214706	56/172 (33%)