DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13893 and Ttpa

DIOPT Version :9

Sequence 1:	NP_612042.3	Gene:	CG13893 / 38074	FlyBaseID:	FBgn0035146	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_037180.1	Gene:	Ttpa / 25571	RGDID:	3915	Length:	278	Species:	Rattus norvegicus

Alignment Length:	275	Identity:	59/275 - (21%)
Similarity:	118/275 - (42%)	Gaps:	66/275 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GPL--PEISEE-------QRAILEKFRKQMDDALVGTHD---DYFLVRWLRARKWNLEAAEKMLR 55
            ||:  .:::|:       |..:.|..|:..::.:..|..   |.||:|:||||.::|:.|.::::
  Rat     7 GPVVGKQLNEQPDHSPLVQPGLAELRRRAQEEGVPETPQPLTDAFLLRFLRARDFDLDLAWRLMK 71

  Fly    56 ASLKTRAMWNVDNIEKW--DPPKALQEYLPYGLMGY------------DNEGSPVLVCPFANFDM 106
                        |..||  :.|:...:..|..::|.            |..||.||:...:.:|
  Rat    72 ------------NYYKWRAECPELSADLHPRSILGLLKAGYHGVLRSRDPTGSRVLIYRISYWD- 123

  Fly   107 WGMMHCVTRFEFQKYLVLLLERFMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAWR--PAAEC 169
               ....|.::.  :.|.|:...:.:...::|::|.:|     .||::       .|:  .|.:.
  Rat   124 ---PKVFTAYDV--FRVSLITSELIVQEVETQRNGVKA-----IFDLE-------GWQISHAFQI 171

  Fly   170 VISTVKQYEA----NFPELLKMCYIINAPKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQL 230
            ..|..|:..|    :||..::..::||.|.:|...|:::|.||.|....:|.::.   :.::..|
  Rat   172 TPSVAKKIAAVVTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKGRIHLHG---NNYKSSL 233

  Fly   231 FSHVNRKAFPKAWGG 245
            ..|. ....|..:||
  Rat   234 LQHF-PDILPLEYGG 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	13/43 (30%)
		SEC14	75..246	CDD:238099	39/189 (21%)
		GOLD_2	303..381	CDD:290608
Ttpa	NP_037180.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22		3/14 (21%)
		CRAL_TRIO_N	25..73	CDD:215024	14/59 (24%)
		CRAL_TRIO	99..248	CDD:395525	36/171 (21%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	208..211		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810