DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13893 and spo20

DIOPT Version :9

Sequence 1:	NP_612042.3	Gene:	CG13893 / 38074	FlyBaseID:	FBgn0035146	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_593003.1	Gene:	spo20 / 2543628	PomBaseID:	SPAC3H8.10	Length:	286	Species:	Schizosaccharomyces pombe

Alignment Length:	270	Identity:	76/270 - (28%)
Similarity:	117/270 - (43%)	Gaps:	38/270 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGPLP------------EISEEQRAILEKFRKQMDD-ALVGTHDDYFLVRWLRARKWNLEAAEK 52
            :|.|.|            .::..|:|.|:..|.::.. ......||..|:|:|||||:||:.:.:
pombe     5 ISDPYPLTNPNAPLGHPGHLNSTQQATLDSMRLELQKLGYTERLDDATLLRFLRARKFNLQQSLE 69

  Fly    53 MLRASLKTRAMWNVDNIEK---WDPPKALQEYLPYGLMGYDNEGSPVLVCPFANFDMWGMMHCVT 114
            |.....|.|..:.||::.|   :|..:|:.:|.|......|.:|.||.|....|.|:..:....|
pombe    70 MFIKCEKWRKEFGVDDLIKNFHYDEKEAVSKYYPQFYHKTDIDGRPVYVEQLGNIDLKKLYQITT 134

  Fly   115 RFEFQKYLV-----LLLERFMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAWRPAAECVISTV 174
            .....:.||     |.|:||...    |:|.|..........|::.|.:      .:...|.|.:
pombe   135 PERMMQNLVYEYEMLALKRFPAC----SRKAGGLIETSCTIMDLKGVGI------TSIHSVYSYI 189

  Fly   175 KQYEA----NFPELLKMCYIINAPKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVN 235
            :|..:    .:||.:...|:||||..||.|||::|.||||.|..||.|..|   .::..|...:.
pombe   190 RQASSISQDYYPERMGKFYVINAPWGFSSAFNLIKGFLDEATVKKIHILGS---NYKSALLEQIP 251

  Fly   236 RKAFPKAWGG 245
            ....|...||
pombe   252 ADNLPAKLGG 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	14/41 (34%)
		SEC14	75..246	CDD:238099	51/180 (28%)
		GOLD_2	303..381	CDD:290608
spo20	NP_593003.1	CRAL_TRIO_N	29..74	CDD:215024	15/44 (34%)
spo20	NP_593003.1	SEC14	94..264	CDD:214706	51/181 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	81	1.000	Inparanoid score	I1844
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000197
OrthoInspector	1	1.000	-	-		otm47220
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1304
SonicParanoid	1	1.000	-	-		X1090
TreeFam	0	0.000	Not matched by this tool.
	8	7.890