Protein Alignment CG13893 and SEC14L2

DIOPT Version :9

• Sequence 1: NP_612042.3
• Gene: CG13893 / 38074
• FlyBaseID: FBgn0035146
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_036561.1
• Gene: SEC14L2 / 23541
• HGNCID: 10699
• Length: 403
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 126/402 - (31%)
• Similarity: 224/402 - (55%)
• Gaps: 23/402 - (5%)

  Fly     1 MSGPLPEISEEQRAILEKFRKQMDDAL--VGTHDDYFLVRWLRARKWNLEAAEKMLRASLKTRAM 63
            |||.:.::|..|:..|.|||:.:.|.|  :...|||||:||||||.::|:.:|.|||..::.|..
Human     1 MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQ 65

  Fly    64 WNVDNIEKWDPPKALQEYLPYGLMGYDNEGSPVLVCPFANFDMWGMMHCVTRFEFQKYLVLLLER 128
            .::|||..|.||:.:|:||..|:.|||.:|.||........|..|::...::.:..:..:...|.
Human    66 KDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECEL 130

  Fly   129 FMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAWRPAAECVISTVKQYEANFPELLKMCYIINA 193
            .::....|:.|.|.:...:.:.:|.:.:.|| :.|:||.|.....:..:|.|:||.||..:::.|
Human   131 LLQECAHQTTKLGRKVETITIIYDCEGLGLK-HLWKPAVEAYGEFLCMFEENYPETLKRLFVVKA 194

  Fly   194 PKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVNRKAFPKAWGGEMVDRNGDPQCKA 258
            ||||.||:|::|.||.|:|..||::..:   .|:|.|..|::....|..:||.|.|.:|:|:||:
Human   195 PKLFPVAYNLIKPFLSEDTRKKIMVLGA---NWKEVLLKHISPDQVPVEYGGTMTDPDGNPKCKS 256

  Fly   259 LMVWGGKLPEELYI-DQSSQQSDRDFVEAQVPKGDKLKLHFKVNVEEQKILSWEFRTFDYDIKFG 322
            .:.:||.:|.:.|: ||..||.:.   ..|:.:|...::.::: :....:|.|:|.:...|:.||
Human   257 KINYGGDIPRKYYVRDQVKQQYEH---SVQISRGSSHQVEYEI-LFPGCVLRWQFMSDGADVGFG 317

  Fly   323 IYSVDDKTGEKRSEVPLGTVYSNE------MDEIGYISTRPNTTYTVVFDNSASYLRSKKLRYWV 381
            |: :..|.||::....:..|..|:      :.|.|.::......|.:.|||:.|::.:||:.:.|
Human   318 IF-LKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNTYSFIHAKKVNFTV 381

  Fly   382 DLI-----SEEE 388
            :::     |||:
Human   382 EVLLPDKASEEK 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	22/42 (52%)
		SEC14	75..246	CDD:238099	51/170 (30%)
		GOLD_2	303..381	CDD:290608	21/83 (25%)
SEC14L2	NP_036561.1	CRAL_TRIO_N	13..59	CDD:215024	22/45 (49%)
		SEC14	76..244	CDD:214706	52/171 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151941
Domainoid	1	1.000	63	0.304	Domainoid score	I10238
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	224	1.000	Inparanoid score	I3520
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52454
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	1	1.000	-	-		FOG0000197
OrthoInspector	1	1.000	-	-		otm41197
orthoMCL	1	0.900	-	-		OOG6_102488
Panther	1	1.100	-	-	O	PTHR23324
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1304
SonicParanoid	1	1.000	-	-		X1090
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.840