DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kah and CRZ1

DIOPT Version :9

Sequence 1:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_014371.1	Gene:	CRZ1 / 855704	SGDID:	S000004972	Length:	678	Species:	Saccharomyces cerevisiae

Alignment Length:	272	Identity:	64/272 - (23%)
Similarity:	114/272 - (41%)	Gaps:	69/272 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTKDQQATPIPEELYNLTQLAEVTLSVGPLVTDEVKPLPLYASSDDDSNYYSHKVFDRRKLRRCT 65
            ::.|::|..|......|.::|::              ||   ||::|:|   .:.:|
Yeast   428 ISPDEKAKSISANREKLLEMADL--------------LP---SSENDNN---RERYD-------- 464

  Fly    66 ISDSNSCASSSSSSTSSRQSSEDHLGLQGHSSVHHHHGEQGEI-----LNSTS----LLEDEHIC 121
             :||.:..::.:||..:..::.::| |.....:     |.|.:     |:.||    :|.|....
Yeast   465 -NDSKTSYNTINSSNFNEDNNNNNL-LTSKPKI-----ESGIVNIKNELDDTSKDLGILLDIDSL 522

  Fly   122 PECGKKYSTSSNLARHRQTHRSIMDKKARHCPYCEKVYVSMPAYSMHVRTHNQ----GCECQFCG 182
            .:..:|....::.......:.:...||..:....:.|            |:|:    ...|..||
Yeast   523 GQFEQKVGFKNDDNHENNDNGTFSVKKNDNLEKLDSV------------TNNRKNPANFACDVCG 575

  Fly   183 KRFSRPWLLQGHIRTHTGEKPFKCGVCEKAFADKSNLRAHIQTHSNTKPHTCA---------RCG 238
            |:|:||:.|:.|:||||.|:||.|.:|.||||.:.:.:.|...|:..|.:.|.         .||
Yeast   576 KKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCG 640

  Fly   239 KAFALKSYLYKH 250
            |.||....|.:|
Yeast   641 KKFARSDALGRH 652

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	1/21 (5%)
		C2H2 Zn finger	121..141	CDD:275368	1/19 (5%)
		zf-C2H2	176..198	CDD:278523	10/21 (48%)
		C2H2 Zn finger	178..198	CDD:275368	10/19 (53%)
		zf-H2C2_2	191..214	CDD:290200	13/22 (59%)
		zf-C2H2	204..226	CDD:278523	8/21 (38%)
		C2H2 Zn finger	206..226	CDD:275368	7/19 (37%)
		zf-H2C2_2	218..242	CDD:290200	7/32 (22%)
		C2H2 Zn finger	234..250	CDD:275368	7/24 (29%)
CRZ1	NP_014371.1	COG5048	139..617	CDD:227381	54/235 (23%)
		C2H2 Zn finger	571..591	CDD:275368	10/19 (53%)
		C2H2 Zn finger	599..619	CDD:275368	7/19 (37%)
		C2H2 Zn finger	627..655	CDD:275368	8/26 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100