DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kah and SCRT2

DIOPT Version :9

Sequence 1:NP_612040.1 Gene:Kah / 38072 FlyBaseID:FBgn0035144 Length:442 Species:Drosophila melanogaster
Sequence 2:NP_149120.1 Gene:SCRT2 / 85508 HGNCID:15952 Length:307 Species:Homo sapiens


Alignment Length:283 Identity:116/283 - (40%)
Similarity:149/283 - (52%) Gaps:46/283 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 IPEELYNLTQ-----LAEVTLSVGPLVTDEVKPLPLYASSDDDSNYYSHKVFDRRKLRRCTISDS 69
            :|...|:..|     ||....:..|...:|      |:..:...:..|.:.|    .....::||
Human    51 LPPSSYDADQKPGLELAPAEPAYPPAAPEE------YSDPESPQSSLSARYF----RGEAAVTDS 105

  Fly    70 NSCASSSSSSTSSRQ----------SSEDHLGLQGHSSVHHHHGEQGEILNSTSLLEDEHICPEC 124
            .|..:...|...||:          .|.|..|..|.:      |..|.....    ...|.|.||
Human   106 YSMDAFFISDGRSRRRRGGGGGDAGGSGDAGGAGGRA------GRAGAQAGG----GHRHACAEC 160

  Fly   125 GKKYSTSSNLARHRQTHRSIMDKKARHCPYCEKVYVSMPAYSMHVRTHNQGCECQFCGKRFSRPW 189
            ||.|:|||||:||:|||||:..:.||.||.|.|.||||||.:||:.|||...:|..|||.|||||
Human   161 GKTYATSSNLSRHKQTHRSLDSQLARKCPTCGKAYVSMPALAMHLLTHNLRHKCGVCGKAFSRPW 225

  Fly   190 LLQGHIRTHTGEKPFKCGVCEKAFADKSNLRAHIQTHSNTKPHTCARCGKAFALKSYLYKHEESS 254
            |||||:|:|||||||.|..|.|||||:||||||:||||..|.:.|.:|.|:|||||||:||.|::
Human   226 LLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKSFALKSYLHKHCEAA 290

  Fly   255 CMKNRGGVPGSGAASGNRPPSSP 277
            |.|           :...||.:|
Human   291 CAK-----------AAEPPPPTP 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KahNP_612040.1 zf-C2H2 119..141 CDD:278523 15/21 (71%)
C2H2 Zn finger 121..141 CDD:275368 14/19 (74%)
zf-C2H2 176..198 CDD:278523 15/21 (71%)
C2H2 Zn finger 178..198 CDD:275368 15/19 (79%)
zf-H2C2_2 191..214 CDD:290200 16/22 (73%)
zf-C2H2 204..226 CDD:278523 15/21 (71%)
C2H2 Zn finger 206..226 CDD:275368 14/19 (74%)
zf-H2C2_2 218..242 CDD:290200 13/23 (57%)
C2H2 Zn finger 234..250 CDD:275368 10/15 (67%)
SCRT2NP_149120.1 SNAG domain. /evidence=ECO:0000250 1..20
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 34..90 8/44 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 116..148 8/37 (22%)
C2H2 Zn finger 157..177 CDD:275368 14/19 (74%)
COG5048 <210..>277 CDD:227381 43/66 (65%)
C2H2 Zn finger 214..234 CDD:275368 15/19 (79%)
zf-H2C2_2 227..250 CDD:290200 16/22 (73%)
C2H2 Zn finger 242..262 CDD:275368 14/19 (74%)
zf-H2C2_2 254..278 CDD:290200 13/23 (57%)
C2H2 Zn finger 270..286 CDD:275368 10/15 (67%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165147578
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2462
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D545011at33208
OrthoFinder 1 1.000 - - FOG0000984
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR24388
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3156
SonicParanoid 1 1.000 - - X1445
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
87.880

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