DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kah and SCRT1

DIOPT Version :9

Sequence 1:NP_612040.1 Gene:Kah / 38072 FlyBaseID:FBgn0035144 Length:442 Species:Drosophila melanogaster
Sequence 2:NP_112599.2 Gene:SCRT1 / 83482 HGNCID:15950 Length:348 Species:Homo sapiens


Alignment Length:295 Identity:127/295 - (43%)
Similarity:158/295 - (53%) Gaps:38/295 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 PIPEELYNLTQLAEVTLSVGPLVTDEVKPLPL-----------YASSDDD-SNYYSHKVF---DR 58
            |.||.:|    .|.|...:||.......| |.           |.:.|.. |..|:...|   |.
Human    63 PSPEPMY----AAAVRGELGPAAAGSAPP-PTPRPELATAAGGYINGDAAVSEGYAADAFFITDG 122

  Fly    59 RKLRRCTISDSNSCASSSSSSTSSRQSSEDHLGLQGHSSVHHHHGEQGEILNSTSL--------- 114
            |..|:.  |::.:.|:.|::|.::........|..|..|:....|.:|........         
Human   123 RSRRKA--SNAGAAAAPSTASAAAPDGDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEARAGPGAA 185

  Fly   115 -LEDEHICPECGKKYSTSSNLARHRQTHRSIMDKKARHCPYCEKVYVSMPAYSMHVRTHNQGCEC 178
             ....|.|.||||.|:|||||:||:|||||:..:.||.||.|.||||||||.:||:.||:...:|
Human   186 GAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLTHDLRHKC 250

  Fly   179 QFCGKRFSRPWLLQGHIRTHTGEKPFKCGVCEKAFADKSNLRAHIQTHSNTKPHTCARCGKAFAL 243
            ..|||.||||||||||:|:|||||||.|..|.|||||:||||||:||||..|...|.||.|:|||
Human   251 GVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFAL 315

  Fly   244 KSYLYKHEESSCMKNRGGVPGSGAASGNRPPS-SP 277
            ||||.||.||:|.|...|.|.:.|     ||. ||
Human   316 KSYLNKHYESACFKGGAGGPAAPA-----PPQLSP 345

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KahNP_612040.1 zf-C2H2 119..141 CDD:278523 15/21 (71%)
C2H2 Zn finger 121..141 CDD:275368 14/19 (74%)
zf-C2H2 176..198 CDD:278523 15/21 (71%)
C2H2 Zn finger 178..198 CDD:275368 15/19 (79%)
zf-H2C2_2 191..214 CDD:290200 16/22 (73%)
zf-C2H2 204..226 CDD:278523 15/21 (71%)
C2H2 Zn finger 206..226 CDD:275368 14/19 (74%)
zf-H2C2_2 218..242 CDD:290200 14/23 (61%)
C2H2 Zn finger 234..250 CDD:275368 11/15 (73%)
SCRT1NP_112599.2 SNAG domain. /evidence=ECO:0000250 1..20
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 129..189 9/59 (15%)
C2H2 Zn finger 224..244 CDD:275368 13/19 (68%)
COG5048 <245..>313 CDD:227381 44/67 (66%)
C2H2 Zn finger 250..270 CDD:275368 15/19 (79%)
C2H2 Zn finger 278..298 CDD:275368 14/19 (74%)
C2H2 Zn finger 306..322 CDD:275368 11/15 (73%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165147577
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2462
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D545011at33208
OrthoFinder 1 1.000 - - FOG0000984
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24388
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3156
SonicParanoid 1 1.000 - - X1445
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
87.880

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