Protein Alignment Kah and PLAGL1

DIOPT Version :10

• Sequence 1: NP_612040.1
• Gene: Kah / 38072
• FlyBaseID: FBgn0035144
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: NP_006709.2
• Gene: PLAGL1 / 5325
• HGNCID: 9046
• Length: 463
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 87/395 - (22%)
• Similarity: 143/395 - (36%)
• Gaps: 109/395 - (27%)

  Fly   104 EQGEILNSTSLLEDEHIC--PECGKKYSTSSNLARHRQTHRSIMDKKARHCPYCEKVYVSMPAYS 166
            |:..|.|.:...|..:.|  |:|||.:.:...|.||..||   ..:|:..|.:|||.:.......
Human    17 EKFTIHNYSHSRERPYKCVQPDCGKAFVSRYKLMRHMATH---SPQKSHQCAHCEKTFNRKDHLK 78

  Fly   167 MHVRTHNQ-----GCE---------------------------CQFCGKRFSRPWLLQGHIRTHT 199
            .|::||:.     |||                           |..|........:|..|::.|.
Human    79 NHLQTHDPNKMAFGCEECGKKYNTMLGYKRHLALHAASSGDLTCGVCALELGSTEVLLDHLKAHA 143

  Fly   200 GEKP--------FKCGVCEKAFADKSNLRAHIQTHSNTKPHTCARCGKAFALKSYLYKHEESSCM 256
            .|||        .:|..||:.|..:.::|.|:..|:..|...|..|.:.|..|.:|.:|.:
Human   144 EEKPPSGTKEKKHQCDHCERCFYTRKDVRRHLVVHTGCKDFLCQFCAQRFGRKDHLTRHTK---- 204

  Fly   257 KNRGGVPGSGAASGNRPPSSPKRQQAEVTSGTISALAPGSPAAAVCAAS-------DSAKSTLAN 314
                           :..|....:::..|...:|.....||:..:.||:       .||::.||:
Human   205 ---------------KTHSQELMKESLQTGDLLSTFHTISPSFQLKAAALPPFPLGASAQNGLAS 254

  Fly   315 KLLQKE-----KDRRQAAMAFQGFPAGPEVTAYSHATSAQEEYEKFKRINVIQPKVMPHRVPSLY 374
            .|..:.     ....|||...|..   ||..|..|.:              :.|...|..:|:..
Human   255 SLPAEVHSLTLSPPEQAAQPMQPL---PESLASLHPS--------------VSPGSPPPPLPNHK 302

  Fly   375 QDLLPNRHVPLA-LPLAMPYHFQGQATSTGQSDPTSVQEQPVDFSPKNNFTHSAKTSP-FELT-G 436
            .:.....:.||| |||        :|.:.|..:.:..::.|:. .|::    ..|.:| |:|. |
Human   303 YNTTSTSYSPLASLPL--------KADTKGFCNISLFEDLPLQ-EPQS----PQKLNPGFDLAKG 354

  Fly   437 NYAMV 441
            |...|
Human   355 NAGKV 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	C2H2 Zn finger	121..141	CDD:275368	8/21 (38%)
		zf-C2H2	176..198	CDD:395048	6/48 (13%)
		C2H2 Zn finger	178..198	CDD:275368	4/19 (21%)
		zf-H2C2_2	191..214	CDD:463886	9/30 (30%)
		zf-C2H2	204..226	CDD:395048	6/21 (29%)
		C2H2 Zn finger	206..226	CDD:275368	6/19 (32%)
		C2H2 Zn finger	234..250	CDD:275368	5/15 (33%)
PLAGL1	NP_006709.2	C2H2 Zn finger	6..26	CDD:275368	3/8 (38%)
		SFP1	<29..109	CDD:227516	22/82 (27%)
		C2H2 Zn finger	34..56	CDD:275368	8/21 (38%)
		zf-H2C2_2	49..73	CDD:463886	10/26 (38%)
		C2H2 Zn finger	64..84	CDD:275368	5/19 (26%)
		C2H2 Zn finger	93..113	CDD:275368	2/19 (11%)
		C2H2 Zn finger	122..142	CDD:275368	4/19 (21%)
		C2H2 Zn finger	158..178	CDD:275368	6/19 (32%)
		C2H2 Zn finger	186..207	CDD:275368	6/39 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	268..306		11/54 (20%)