DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kah and sqz

DIOPT Version :9

Sequence 1:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	394	Identity:	101/394 - (25%)
Similarity:	155/394 - (39%)	Gaps:	98/394 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 SSSSSTSSRQSSEDHLGLQGHSSVHHHHGEQGEILNSTSLLEDEHICPECGKKYSTSSNLARHRQ 139
            ||:|.:.|..||.:....:|       .|:|.:          .:.|..|.|.::.||.|::|.:
  Fly   131 SSASGSGSNGSSPEEESRRG-------DGDQAK----------PYKCGSCSKSFANSSYLSQHTR 178

  Fly   140 THRSIMDKKARHCPYCEKVYVSMPAYSMHVRTHN----QGCECQFCGKRFSRPWLLQGHIRTHTG 200
            .|..|   |...|..|::.:..:.....|:|||.    ..|....|.|.||:...||.|.|.|..
  Fly   179 IHLGI---KPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSHSRCHQT 240

  Fly   201 EKPFKCGVCEKAFADKSNLRAHIQTHSNT---KPHTCARCGKAFALKSYLYKHEESSCMK----- 257
            :|||||..|.|.|:|:..|..||..|.::   |.|.|..|||::..::||.||.:....|
  Fly   241 DKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQKHLQKHAEKAEKQQ 305

  Fly   258 ---------NRGGVPGSGAASGNRPPSSPKRQQAEVTSGTISALAPGSPAAAVCA--ASDSAKST 311
                     ::..||.||..      .:.:||            |.....||..|  .:|||.::
  Fly   306 HRHTAQVAAHQQHVPASGIG------LNLQRQ------------AMNDVNAAYWAKMGADSAAAS 352

  Fly   312 LANKLLQKEKDRRQAAMAFQGFP-AGPEVTAYSHATSAQEEYEKFKRINVIQPKVMPHRVPSLYQ 375
            ||..:.|:             .| ||.:  .|.:..|.|:::::      .|.:::.|:   ...
  Fly   353 LAEAIQQQ-------------LPQAGGQ--PYGNFASLQQQHQQ------QQQELLHHQ---RLA 393

  Fly   376 DLLPNRHVP--------LALPLAMP-YHFQGQATSTGQSDPTSVQEQPVDFSPKNNFTHSAKTSP 431
            |...:.|.|        |.|..:.| :|.|.|...  |....:.|:|.....|.....:||.| |
  Fly   394 DTPGHSHSPHEEAAGEDLVLRQSTPQHHLQQQQQQ--QQQQQAQQQQQAQHQPSPGPGNSAFT-P 455

  Fly   432 FELT 435
            ...|
  Fly   456 LSAT 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	7/21 (33%)
		C2H2 Zn finger	121..141	CDD:275368	7/19 (37%)
		zf-C2H2	176..198	CDD:278523	9/21 (43%)
		C2H2 Zn finger	178..198	CDD:275368	8/19 (42%)
		zf-H2C2_2	191..214	CDD:290200	12/22 (55%)
		zf-C2H2	204..226	CDD:278523	10/21 (48%)
		C2H2 Zn finger	206..226	CDD:275368	8/19 (42%)
		zf-H2C2_2	218..242	CDD:290200	10/26 (38%)
		C2H2 Zn finger	234..250	CDD:275368	6/15 (40%)
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	7/19 (37%)
		zf-H2C2_2	172..197	CDD:290200	7/27 (26%)
		zf-C2H2	186..208	CDD:278523	4/21 (19%)
		C2H2 Zn finger	188..208	CDD:275368	4/19 (21%)
		zf-C2H2_8	191..271	CDD:292531	28/79 (35%)
		zf-H2C2_2	200..227	CDD:290200	8/26 (31%)
		C2H2 Zn finger	216..238	CDD:275368	9/21 (43%)
		C2H2 Zn finger	246..266	CDD:275368	8/19 (42%)
		C2H2 Zn finger	277..297	CDD:275368	8/19 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840