DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kah and M1BP

DIOPT Version :9

Sequence 1:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	260	Identity:	67/260 - (25%)
Similarity:	108/260 - (41%)	Gaps:	33/260 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TPIPEELYNLTQLAEVTLSVGPLVTDEVKPLPLYASSDDDSNYY----SHKVFDRRKLRRCTISD 68
            ||..:|:|...|  |:.|.......|:.|       .:.|:.||    .|...| ........:|
  Fly   114 TPDDDEVYATYQ--EIVLEEPKEEIDDTK-------VEYDNTYYEVAEGHAGED-DAASLIEEAD 168

  Fly    69 SNSCASSSSSSTSSRQSSEDHLGLQGHSSVHHHHGEQGEILNSTSLLEDEH-----ICPECG--K 126
            .:|..:.......:.:..||...:.|..:..:.:....|:....::|:||:     :..:|.  .
  Fly   169 YDSIMAEDEEQQQTLELDEDTELIVGDVNDAYVYDSDDEVAVLDNVLDDEYEHENIVVKKCSLPP 233

  Fly   127 KYSTSSNLARHRQTHRSIMDKKARHCPYCEKVYVSMPAYSMHVRTH--NQGCECQFCGKRFSRPW 189
            |....|:.||.|.|....:      |..|........|:.:|.|.|  ::...|:.|..||....
  Fly   234 KPKVRSDDARRRGTGGVYI------CEQCGNHIKGRMAFELHCRRHRGDKQFGCELCQSRFCTTS 292

  Fly   190 LLQGHIRTHTGEKPFKCGVCEKAFADKSNLRAHIQTHSNTKPHTCARCGKAFA----LKSYLYKH 250
            .|:.|:|.||||:||.|..|.:.|.|.:....|.:||:|.:|:.|..|||||.    ||:::..|
  Fly   293 ELKRHMRKHTGERPFACKYCGRCFTDYTTRVKHERTHTNERPYVCGTCGKAFTTGYILKNHMLIH 357

Fly 251 250
Fly 358 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	6/28 (21%)
		C2H2 Zn finger	121..141	CDD:275368	6/21 (29%)
		zf-C2H2	176..198	CDD:278523	7/21 (33%)
		C2H2 Zn finger	178..198	CDD:275368	7/19 (37%)
		zf-H2C2_2	191..214	CDD:290200	11/22 (50%)
		zf-C2H2	204..226	CDD:278523	6/21 (29%)
		C2H2 Zn finger	206..226	CDD:275368	5/19 (26%)
		zf-H2C2_2	218..242	CDD:290200	10/23 (43%)
		C2H2 Zn finger	234..250	CDD:275368	8/19 (42%)
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871
		C2H2 Zn finger	253..273	CDD:275368	5/19 (26%)
		COG5048	276..>331	CDD:227381	20/54 (37%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		zf-H2C2_2	293..317	CDD:290200	11/23 (48%)
		C2H2 Zn finger	309..329	CDD:275368	5/19 (26%)
		zf-H2C2_2	324..346	CDD:290200	11/21 (52%)
		C2H2 Zn finger	337..357	CDD:275368	8/19 (42%)
		zf-H2C2_2	350..372	CDD:290200	3/8 (38%)
		C2H2 Zn finger	365..383	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100